Human equivalent age based on size and other factors.
Karyogram (Chromosome painting)
These clinical genetic traits can inform clinical decisions and diagnoses. These traits do not predict a disease state or increased risk for disease. We currently assess one clinical trait: Alanine Aminotransferase Activity.
Alanine Aminotransferase Activity result: Low Normal
Jeddak has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Jeddak has this genotype, as ALT is often used as an indicator of liver health and Jeddak is likely to have a lower than average resting ALT activity. As such, an increase in Jeddak’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
More information on Alanine Aminotransferase Activity:
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a sensitive measure of liver health. Dogs with two ancestral G alleles show "normal" activity. Dogs that have one or two copies of the derived A allele may have lower resting levels of ALT activity, known as "low normal". If your dog's result is "low normal" then when a blood chemistry panel is being interpreted the values that you and your veterinarian consider "normal" may need to be adjusted. Please note that neither a "normal" nor a "low normal" result for this predicts a disease state or increased risk for liver disease. Moreover, this mutation does not associate with increased levels of ALT: If your dog has high ALT levels, please consult your veterinarian.
How to interpret these results:
AT RISK status: Testing positive (AT RISK) is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.
CARRIER status: This indicates the dog has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but
is important to bear in mind if the dog ever has offspring.
Not AT RISK for any conditions tested.
System: Other Systems
Condition: Autosomal Recessive Amelogenesis Imperfecta (Italian Greyhound Variant)
A disease of the tooth enamel production, affected dogs have characteristic small, pointy teeth that discolor rapidly. Amelogenesis is the formation and deposition of enamel, a hard, impenetrable substance which protects teeth from acid and traumatic degradation. In the young dog, specialized cells called ameloblasts gather over the developing tooth and deposit enamel. Ameloblasts are left behind in the tooth socket as soon as a tooth erupts, which is why enamel does not renew with time. In ARAI, a defect in enamel production leads uneven enamel laydown, leading to yellowing of the underlying tooth. Teeth are also unusually small and pointy with large gaps between them. Dogs may be prone to more dental disease with this condition and should be brought to the vet for regular dental checkups.
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