Owner Name: Hannah Williams
Dog Name: Winnie
Sex: Female (intact)
Date of birth: 02/10/22
Breed type: N/A
Breed: Golden Retriever
Breed registration: American Kennel Club (AKC)
Genetic breed identification:
Breed ancestry:Golden Retriever: 100.0%
Predicted adult weight: 60 lbs
Calculated from 17 size genes.
Life stage: Puppy
Based on date of birth provided.
These clinical genetic tools can inform clinical decisions and diagnoses. These tools do not predict increased risk for disease.
Alanine Aminotransferase Activity (GPT)
Winnie's baseline ALT level may be Low Normal
Winnie has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Winnie has this genotype, as ALT is often used as an indicator of liver health and Winnie is likely to have a lower than average resting ALT activity. As such, an increase in Winnie’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Genetic testing is the only way to provide your veterinarian with this clinical tool.
Veterinarians may recommend blood work to establish a baseline ALT value for healthy dogs with one or two copies of this variant.
If Winnie inherited any of the variants that we tested, they will be listed at the top of the Health Report section, along with a description of how to interpret this result. We also include all of the variants that we tested Winnie for that we did not detect the risk variant for.A genetic test is not a diagnosis
This genetic test does not diagnose a disease. Please talk to your vet about your dog’s genetic results, or if you think that your pet may have a health condition or disease.
Winnie is not at increased risk for the genetic health conditions that Embark tests.
Breed-Relevant Genetic Conditions 11 variants not detected
Additional Genetic Conditions 222 variants not detected
Winnie did not have the variants that we tested for, that are relevant to her breed:
Winnie did not have the variants that we tested for, in the following conditions that the potential effect on dogs with Winnie’s breed may not yet be known.
Coefficient of Inbreeding (COI)
- Genetic Result:
Our genetic COI measures the proportion of your dog’s genome (her genes) where the genes on the mother’s side are identical by descent to those on the father’s side. The higher your dog’s coefficient of inbreeding (the percentage), the more inbred your dog is.
Your Dog’s COI
This graph represents where your dog’s inbreeding levels fall on a scale compared to both dogs with a similar breed makeup to her (the blue bars) and all purebred dogs (the grey line).
More on the Science
Embark scientists, along with our research partners at Cornell University, have shown the impact of inbreeding on longevity and fertility and developed a state-of-the-art, peer-reviewed method for accurately measuring COI and predicting average COI in litters.
- Sams & Boyko 2019 "Fine-Scale Resolution of Runs of Homozygosity Reveal Patterns of Inbreeding and Substantial Overlap with Recessive Disease Genotypes in Domestic Dogs"
- Chu et al 2019 "Inbreeding depression causes reduced fecundity in Golden Retrievers"
- Yordy et al 2019 "Body size, inbreeding, and lifespan in domestic dogs"
Embark Veterinary is a canine genetics company offering research-grade genetic tests to pet owners and breeders. Every Embark test examines over 200,000 genetic markers, and provides results for over 230 genetic health conditions, breed identification, clinical tools, and more.
Embark is a research partner of the Cornell University College of Veterinary Medicine and collaborates with scientists and registries to accelerate genetic research in canine health. We make it easy for customers and vets to understand, share and make use of their dog’s unique genetic profile to improve canine health and happiness.
Learn more at embarkvet.com
Veterinarians and hospitals can send inquiries to firstname.lastname@example.org.