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These clinical genetic tools can inform clinical decisions and diagnoses. These tools do not predict increased risk for disease.
Thor has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Thor has this genotype, as ALT is often used as an indicator of liver health and Thor is likely to have a lower than average resting ALT activity. As such, an increase in Thor’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Genetic testing is the only way to provide your veterinarian with this clinical tool.
Veterinarians may recommend blood work to establish a baseline ALT value for healthy dogs with one or two copies of this variant.
If Thor inherited any of the variants that we tested, they will be listed at the top of the Health Report section, along with a description of how to interpret this result. We also include all of the variants that we tested Thor for that we did not detect the risk variant for.A genetic test is not a diagnosis
This genetic test does not diagnose a disease. Please talk to your vet about your dog’s genetic results, or if you think that your pet may have a health condition or disease.
Thor inherited one variant that you should learn more about.
This result should not impact Thor’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.
Your dog carries this variant and will pass it on to ~50% of his offspring.
The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.
Affected dogs do not usually show signs of DM until they are at least 8 years old.
Definitive diagnosis requires microscopic analysis of the spinal cord after death. However, veterinarians use clues such as genetic testing, breed, age, and other diagnostics to determine if DM is the most likely cause of your dog’s clinical signs.
As dogs are seniors at the time of onset, the treatment for DM is aimed towards increasing their comfort through a combination of lifestyle changes, medication, and physical therapy.
Thor did not have the variants that we tested for, that are relevant to his breed:
Thor did not have the variants that we tested for, in the following conditions that the potential effect on dogs with Thor’s breed may not yet be known.
Our genetic COI measures the proportion of your dog’s genome (her genes) where the genes on the mother’s side are identical by descent to those on the father’s side. The higher your dog’s coefficient of inbreeding (the percentage), the more inbred your dog is.
This graph represents where your dog’s inbreeding levels fall on a scale compared to both dogs with a similar breed makeup to her (the yellow dotted line) and all purebred dogs (the grey line).
Embark scientists, along with our research partners at Cornell University, have shown the impact of inbreeding on longevity and fertility and developed a state-of-the-art, peer-reviewed method for accurately measuring COI and predicting average COI in litters.
Embark Veterinary is a canine genetics company offering research-grade genetic tests to pet owners and breeders. Every Embark test examines over 200,000 genetic markers, and provides results for over 200 genetic health conditions, breed identification, clinical tools, and more.
Embark is a research partner of the Cornell University College of Veterinary Medicine and collaborates with scientists and registries to accelerate genetic research in canine health. We make it easy for customers and vets to understand, share and make use of their dog’s unique genetic profile to improve canine health and happiness.
Learn more at embarkvet.com
Veterinarians and hospitals can send inquiries to firstname.lastname@example.org.