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Zoe

East Asian Village Dog

“Zoe is our 1st rescue. We were told she lived on the streets, found severely beaten. Fractured skull,3 broken feet,ribs & more. We don't think she's a street dog though as she came 100% house trained. She's never barked & doesn't like other dogs. She's also a very picky eater. She always appears tired & sad. The only time she shows any emotion at all is when it's time for her morning walk. Then her excitement is uncontrollable. She shares our bed & after dinner goes directly upstairs to sleep.”

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Genetic Breed Result

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Village dog trace breed analysis

Village dogs often have short stretches of DNA that match purebred dogs, due to a distant common ancestor or a more recent mating between a purebred and a village dog. Zoe has short stretches of DNA in common with these breeds:

What exactly are village dogs?

Village dogs are the free-breeding, free-roaming “outside” dogs found around the world living in and around human settlements big and small. They are also known as island dogs, pariah dogs, or free-ranging dogs.

Many village dog populations precede the formation of modern breed dogs.

They make up about 3/4s of the billion or so dogs living on Earth today. They serve as trash cleaners, sentinels, and even sometimes companions while still retaining much of their freedom. Embark’s founders have studied village dogs on six continents since 2007 in their efforts to understand the history, traits, and health of the domestic dog. Through this work they have discovered the origins of the dog in Central Asia, and also identified genetic regions involved in domestication and local adaptation, such as the high altitude adaptation in Himalayan dogs. Embark is the only dog DNA test that includes diverse village dogs from around the world in its breed reference panel.

So what breeds are in my dog?

In a very real sense, East Asian Village Dog is the actual breed of your dog. Village dogs like this descend from separate lines of dogs than the lines that have been bred into standardized breeds like Labradors and Poodles. If you trace the family tree of Zoe back, you won’t find any ancestral dogs that are part of any of those standardized breeds.

East Asian Village Dog

Many years ago, when wolves began scavenging our hunting camps, they became gradually attuned to human life. Genetic changes in those wolves over time led to tameness, small body size and early age of first reproduction that soon after yielded what we see today in the East Asian village dogs.

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Village dogs have lived just about everywhere across the world for thousands of years. Long before there were any recognized dog breeds, there were village dogs around the fires and trash heaps of early human villages. Zoe is part of this ancient heritage, not descended from a specific breed, but continuing the ancient lineage of dogs that were our first, best friends.

Embark's co-founders studied Village Dogs on six continents in their efforts to understand the history, traits, and health of the domestic dog. Through this work, they discovered evidence for the origins of the dog in Central Asia , and they also identified genetic regions involved in domestication and local adaptation. As a result, Embark has the largest Village Dog reference panel of any canine genetics company.

We compared Zoe's DNA to a global panel of thousands of village dogs. This plot highlights regions of the world where Zoe's DNA is most similar to those village dogs. The areas of darkest red reflect the greatest similarity to our village dog panel.

Village Dog Map
Similarity to village dog groups around the world. Darker red reflects greater similarity.

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Health Summary

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Zoe inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Zoe inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Zoe’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Zoe is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Dilated Cardiomyopathy, DCM1

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Zoe inherited one copy of the variant we tested

What does this result mean?

Our research indicates that this genetic variant is not likely to increase the risk that Zoe will develop this disease.

Scientific Basis

Dogs with similar breeds to Zoe are not likely to have increased risk of developing the disease. Research has indicated increased risk in other breeds that are not found in Zoe.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Zoe inherited one copy of the variant we tested

Why is this important to your vet?

Zoe has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Zoe has this genotype, as ALT is often used as an indicator of liver health and Zoe is likely to have a lower than average resting ALT activity. As such, an increase in Zoe’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Zoe’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1b

Map

B1

Zoe’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1b

Zoe’s Haplotype

Part of the large B1 haplogroup, we see this haplotype in village dogs across the world, including those from Central America, the Middle East, South Asia, and the French Polynesian Islands. Among the 31 breed dogs we see it in, we see it in Poodles, Otterhounds, and Labrador Retrievers. It is also our most commonly-sampled Golden Retriever haplotype!

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Zoe inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Zoe is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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