What is Embark?

Zoe

Mixed Breed

“Adopted from Saving Grace on Sept 12 2016. She speaks "Husky", especially to her human sister Marie.”

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Genetic Breed Result

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Mixed Breed

88.3% Siberian Husky
11.7% Alaskan Malamute
Siberian Husky Siberian Husky
Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.
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Alaskan Malamute Alaskan Malamute
The Alaskan Malamute features a powerful, sturdy body built for stamina and strength. It reigns as one of the oldest dog breeds whose original looks have not been significantly altered. This intelligent canine needs a job and consistent leadership to avoid becoming bored or challenging to handle.
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Genetic Stats

Wolfiness: 2.3 % HIGH Learn More
Predicted Adult Weight: 56 lbs Learn More
Genetic Age: 35 human years Learn More

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Zoe’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Siberian Husky
Alaskan Malamute

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Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Zoe’s breed mix, but this family tree may not be the only possible one.

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Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

0
AT RISK
0
CARRIER
156
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Zoe has two normal alleles at ALT.

Not At Risk

Good news! Zoe did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Zoe does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Zoe’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Zoe is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Zoe tested clear for 5 genetic conditions that are common in her breed mix.
Condition List

Factor VII Deficiency
(F7 Exon 5)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies a…

Seen in Alaskan Malamutes, but not Zoe.

GM1 Gangliosidosis
(GLB1 Exon 15 Alaskan Husky Variant)
Multisystem

An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Seen in Siberian Huskys, but not Zoe.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Siberian Huskys, Alaskan Malamutes, but not Zoe.

Polyneuropathy, NDRG1 Malamute Variant
(NDRG1 Exon 4)
Brain and Spinal Cord

Polyneuropathy is a progressive neurologic disease that causes peripheral nerve dysfution. Peripheral nerves relay messages between the brain and spinal cord to the rest …

Seen in Alaskan Malamutes, but not Zoe.

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Seen in Siberian Huskys, Alaskan Malamutes, but not Zoe.

Other Conditions: Clear of 151

Zoe is clear of 151 other genetic diseases that Embark tests for.

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Family tree

Traits

Maternal Haplotype

Paternal Haplotype

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Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
EE or Ee or ee
K Locus (Dominant Black)
kyky
A Locus (Agouti, Sable)
awaw
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red)
Bb

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Long Haircoat (FGF5)
GG
Shedding (MC5R)
CC
Curly Coat (KRT71)
CT

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Hind Dewclaws (LMBR1)
CT
Blue Eye Color
LINKAGE
Dup/Dup

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NN
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GG
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Zoe’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A18/19/20/21/27/36/94/109

Map

A1b

Zoe’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A18/19/20/21/27/36/94/109

Zoe’s Haplotype

Part of the large A1b haplogroup, we see this haplotype in village dogs in over 25 countries across the world. We have detected this haplotype in lots of breeds, and it occurs most commonly in German Shepherd Dogs, Maltese, English Springer Spaniels, and English Setters.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

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Family tree

Health

Traits

Paternal Haplotype

This 'Paternal Haplotype' tab is for deep ancestral lineage going back thousands of years.

For recent ancestry—"What breeds did my dog inherit from her mom and dad?"—please refer to the Breed, Family Tree, or Summary tab.

The Paternal Haplotype refers to a dog’s deep ancestral lineage stretching back thousands of years, before there were any distinct breeds of dog. We determine the Paternal Haplotype by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Zoe is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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Family tree

Health

Traits

Maternal Haplotype