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Ziggy Female 3

Mixed Ancestry

“A puppy from CURBY X ZIGGY Litter at Curbys Corgis”

Place of Birth

St. George, Utah, USA

Current Location

St. George, Utah, USA

From

St. George, Utah, USA

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Genetic Breed Result

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Pembroke Welsh Corgi

The Pembroke Welsh Corgi is a small, energetic, herding dog that is good with families.

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Cardigan Welsh Corgi

Though less common than their Pembroke cousins, the Cardigan Welsh Corgi is perfectly suited to move cattle, as well as be a smart, driven companion for the right people. This breed is highly trainable, and often compared to a German Shepherd Dog in drive and attitude. Cardigans have the bark of a much bigger dog!

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Dogs Like Ziggy Female 3

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Discover dogs who share a similar breed mix to Ziggy Female 3. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Pembroke Welsh Corgi
Cardigan Welsh Corgi

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Here’s what Ziggy Female 3’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Ziggy Female 3’s breed mix.

Breed Reveal Video

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Health Summary

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Ziggy Female 3 is at increased risk for two genetic health conditions.

And inherited one variant that you should learn more about.

Degenerative Myelopathy, DM

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Ziggy Female 3 inherited both copies of the variant we tested

How to interpret this result

Ziggy Female 3 has two copies of a variant in SOD1 and is at risk for developing DM. As previously stated, this variant is incompletely penetrant, so while it predisposes Ziggy Female 3 to developing DM, other genetic and environmental factors will determine whether Ziggy Female 3 ultimately develops the disease. Please consult your veterinarian to discuss further diagnostic, monitoring, and supportive care options for Ziggy Female 3.'

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Intervertebral Disc Disease (Type I)

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Ziggy Female 3 inherited one copy of the variant we tested

How to interpret this result

Ziggy Female 3 has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Ziggy Female 3 inherited one copy of the variant we tested

Why is this important to your vet?

Ziggy Female 3 has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Ziggy Female 3 has this genotype, as ALT is often used as an indicator of liver health and Ziggy Female 3 is likely to have a lower than average resting ALT activity. As such, an increase in Ziggy Female 3’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

X-linked Severe Combined Immunodeficiency, X-SCID

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Progressive Retinal Atrophy, rcd3

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Exercise-Induced Collapse, EIC

Identified in Cardigan Welsh Corgis and Pembroke Welsh Corgis

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Ziggy Female 3’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C41

Map

C2

Ziggy Female 3’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C41

Ziggy Female 3’s Haplotype

Part of the C2 haplogroup, this haplotype occurs most frequently in mixed breed dogs.

You can often find his haplogroup in the lovable English Bulldog.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Ziggy Female 3 inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Ziggy Female 3 is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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