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Zach

German Pinscher

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“Imported from Belarus”

Place of Birth

Belarus

Current Location

Tennessee, USA

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Registration

American Kennel Club (AKC):

Genetic Breed Result

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German Pinscher

The German Pinscher is a medium-sized breed of dog, a Pinscher type that originated in Germany. The breed is included in the origins of the Dobermann, the Rottweiler, the Miniature Pinscher, the Affenpinscher, the Standard Schnauzer.

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Genetic Stats

Predicted Adult Weight

38 lbs

Genetic Age
28 human years

Based on the date of birth provided

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Health Summary

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Zach has one variant that you should let your vet know about.

ALT Activity

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Zach inherited one copy of the variant we tested

Why is this important to your vet?

Zach has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Zach has this genotype, as ALT is often used as an indicator of liver health and Zach is likely to have a lower than average resting ALT activity. As such, an increase in Zach’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in German Pinschers

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Zach’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A272

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A1e

Zach’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A272

Zach’s Haplotype

Part of the large A1e haplogroup, this haplotype occurs most commonly in Airedale Terriers, Toy Manchester Terriers, Brittanys, and village dogs in Portugal.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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Through Zach’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1

Haplotype

Ha.1

Map

A1

Zach’s Haplogroup

A1 is the male lineage in several breeds that aren't very closely related to each other. Gordon Setters, Newfoundlands, and Miniature Schnauzers all had male founders from this paternal line, and now many males in those breeds carry their Y chromosome. Each of these breeds started in the past 200-300 years, and their founders must have included dogs that trace back to the same male ancestors deeper in dog evolutionary time, stretching all the way back to when dogs were first domesticated in Central Asia about 15,000 years ago. Unlike many Y chromosome (male) lineages found in European and recent American breeds, only one village dog (in Alaska) carries an A1 Y chromosome, indicating that the breeds from this lineage probably didn't travel around the world with European colonization as much as some other breeds.

Ha.1

Zach’s Haplotype

The lone member of the A1 haplogroup, this haplotype occurs in Newfoundlands, Miniature Schnauzers, Gordon Setters, and village dogs in Alaska.

Some other Embark dogs with this haplotype:

The Newfoundland is from the A1 paternal line.

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