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Yeti

Llewellin Setter

“He's a Muppet and his middle name is Spaghetti”

Place of Birth

Enola, Arkansas, USA

Current Location

Denver, Colorado, USA

From

Enola, Arkansas, USA

This dog has been viewed and been given 3 wags

Registration

American Kennel Club (AKC):

Genetic Breed Result

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Llewellin Setter

The Llewellin Setter is widely cherished as one of the best field hunting dogs around. These dogs are well-loved for their hunting prowess, spirit, and sweet dispositions.

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Here’s what Yeti’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Yeti’s breed mix.

Breed Reveal Video

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Health Summary

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Yeti inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Urate Kidney & Bladder Stones

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Yeti inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Yeti’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Yeti is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

ALT Activity

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Yeti inherited one copy of the variant we tested

Why is this important to your vet?

Yeti has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Yeti has this genotype, as ALT is often used as an indicator of liver health and Yeti is likely to have a lower than average resting ALT activity. As such, an increase in Yeti’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Llewellin Setters

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Yeti’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A371

Map

A1d

Yeti’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A371

Yeti’s Haplotype

Part of the large A1d haplogroup, this haplotype occurs most commonly in Labrador Retrievers. It’s a rare find!

The vast majority of Rottweilers have the A1d haplogroup.

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Through Yeti’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.8/32/43/44

Map

A1a

Yeti’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.8/32/43/44

Yeti’s Haplotype

Part of the A1a haplogroup, the H1a.8/32/43/44 haplotype occurs most commonly in Llewellin Setters, Gordon Setters and German Wirehaired Pointers. We've also spotted it in Southeast Asian Village Dogs, European Village Dogs and East Asian Village Dogs.

Dogs with A1a lineage travelled during European Colonial times.

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