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Cosmo

McNab

“Cats are my friends”

Place of Birth

Visalia, CA, USA

Current Location

San Antonio, Texas, USA

From

Visalia, CA, USA

This dog has been viewed and been given 35 wags

Genetic Breed Result

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McNab

McNabs are an interesting breed of herding dog that originated in the Mendocino region of Northern California. It should be noted that it’s quite rare to be able to pinpoint such a specific place of origin for a dog breed from the United States. They were specifically created to withstand the scorching heat of the Mendocino region of California.

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Changes to this dog’s profile
  • On 1/22/2019 changed name from "Wills" to "Cosmo"
  • On 1/22/2019 changed name from "Wills " to "Wills"
Here’s what Cosmo’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Cosmo’s breed mix.
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Health Summary

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Cosmo has one variant that you should let your vet know about.

ALT Activity

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Cosmo inherited one copy of the variant we tested

Why is this important to your vet?

Cosmo has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Cosmo has this genotype, as ALT is often used as an indicator of liver health and Cosmo is likely to have a lower than average resting ALT activity. As such, an increase in Cosmo’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Trapped Neutrophil Syndrome, TNS

Collie Eye Anomaly

Primary Lens Luxation

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Myotonia Congenita

Cobalamin Malabsorption

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Cosmo’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A494

Map

A1a

Cosmo’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A494

Cosmo’s Haplotype

Part of the A1a haplogroup, the A494 haplotype occurs most commonly in McNabs. It's a rare find!

Shar Pei dogs think A1a is the coolest!

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Through Cosmo’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.49

Map

A1a

Cosmo’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.49

Cosmo’s Haplotype

Part of the A1a haplogroup, the H1a.49 haplotype occurs most commonly in McNabs and English Shepherds.

Dogs with A1a lineage travelled during European Colonial times.

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