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WILLOW

French Bulldog

“Just like the Energizer Bunny & Loves to Swim, but Hates the Rain. My Little Sweet Lunatic.”

Place of Birth

Ukraine

Current Location

Toronto, Ontario, Canada

From

Richmond Hill, Ontario, Canada

This dog has been viewed and been given 15 wags

Registration

Microchip: 990000001062918

Genetic Breed Result

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French Bulldog

French Bulldogs, affectionately known by their many fans as Frenchies, are an immensely popular and well-known breed of dog. As their name implies, they are native to France and are the result of a mix between English Bulldogs and local dogs in Paris. They are very popular around the world, earning their place as the 4th most popular dog in the United Kingdom and the 9th most popular dog in the United States.

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Here’s what WILLOW’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain WILLOW’s breed mix.
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Health Summary

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WILLOW is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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WILLOW inherited both copies of the variant we tested

How to interpret this result

WILLOW has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Progressive Retinal Atrophy, crd4/cord1

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WILLOW inherited one copy of the variant we tested

What does this result mean?

This variant should not impact WILLOW’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. WILLOW is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

Dilated Cardiomyopathy, DCM1

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WILLOW inherited one copy of the variant we tested

What does this result mean?

Our research indicates that this genetic variant is not likely to increase the risk that WILLOW will develop this disease.

Scientific Basis

Dogs with similar breeds to WILLOW are not likely to have increased risk of developing the disease. Research has indicated increased risk in other breeds that are not found in WILLOW.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Breed-Relevant Genetic Conditions

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Canine Multifocal Retinopathy, cmr1

Identified in French Bulldogs

Hereditary Cataracts

Identified in French Bulldogs

Urate Kidney & Bladder Stones

Identified in French Bulldogs

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through WILLOW’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A18

Map

A1b

WILLOW’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A18

WILLOW’s Haplotype

Part of the large A1b haplogroup, we see this haplotype in village dogs in Central and South America, as well as French Polynesia. Among the breeds we have detected it in, this haplotype occurs most frequently in Chesapeake Bay Retrievers, Lhasa Apsos, and Pugs.

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that WILLOW inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since WILLOW is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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