A genetic health condition indicates a genetic mutation that increases the risk that
an animal develops a specific disease. For example, having two copies of a
mutation in the PRCD gene increases the risk for developing a type of
Progressive Retinal Atrophy, which is a condition that causes vision loss in dogs.
A clinical trait is a genetic mutation that is NOT associated with increased risk
for a specific disease, but could influence how your veterinarian interprets your dog’s clinical data,
or how they determine your dog’s diagnostic, monitoring, or treatment plan.
Vets are often able to make use of clinical trait information during their practice.
For example, Alanine Aminotransferase (ALT), is a value that vets measure in routine bloodwork.
Learning if your dog's ALT values are normal or not from a DNA test can
help your vet better understand bloodwork results in relation to your dog's liver health.
These clinical traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses
Alanine Aminotransferase Activity result: Low Normal
Willow has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Willow has this genotype, as ALT is often used as an indicator of liver health and Willow is likely to have a lower than average resting ALT activity. As such, an increase in Willow’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.