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Wiley

Carolina Dog

“Wiley is #2 of 3 dogs I'm sending in their DNA that were all purchased from California Carolina Dogs. We belong to a Facebook Group "Native US Dogs" that are working with Dr. Chu. Please send full details on dog DNA so that they can include in their database.”

This dog has been viewed and been given 4 wags

Genetic Breed Result

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Carolina Dog

The Carolina Dog was originally a landrace, rediscovered as a wild dog by Dr. I. Lehr Brisbin, and originally documented in American dog breed publications in the 1920s. Although descended from free-ranging dogs, Carolina Dogs can make good family pets with proper socialization. Carolina Dogs have been a UKC-recognized breed since 1996 and are now part of the AKC Foundation Stock Service (FSS). While debates rage on about the genetic origins of the breed and whether there are still pockets of feral Carolina dogs living in Southeastern US, AKC and UKC Carolina Dogs clearly have a unique and identifiable genetic signature.

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Here’s what Wiley’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Wiley’s breed mix.
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Health Summary

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Wiley has one variant that you should let your vet know about.

ALT Activity

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Wiley inherited both copies of the variant we tested

Why is this important to your vet?

Wiley has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Wiley's ALT activity above their current, healthy, ALT activity. As an increase above Wiley’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Wiley’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A16/17/99/100

Map

A1a

Wiley’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A16/17/99/100

Wiley’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Newfoundlands, German Shepherd Dogs, and Golden Retrievers.

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Wiley inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Wiley is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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