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“Walker”
Mashury Feel It In My Soul

Lancashire Heeler

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“Walker is a Lancashire Heeler.”

Place of Birth

Plattsmouth, NE, USA

Current Location

Lincoln, Nebraska, USA

From

Plattsmouth, NE, USA

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Registration

American Kennel Club (AKC): DN63346301

Genetic Breed Result

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Lancashire Heeler

True to their history as working dogs, Lancashire Heelers are energetic, intelligent, and fun little dogs.

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Changes to this dog’s profile
  • On 9/24/2021 changed name from "Walker" to "Mashury Feel It In My Soul"

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Health Summary

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Walker inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Dilated Cardiomyopathy, DCM2

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Walker inherited one copy of the variant we tested

What does this result mean?

Research indicates that this genetic variant is not likely to increase the risk that Walker will develop this condition.

Scientific Basis

Dogs with Walker’s breed have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of Walker developing clinical disease.

Impact on Breeding

This genetic result should not be the primary factor in your breeding decisions.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Walker inherited one copy of the variant we tested

Why is this important to your vet?

Walker has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Walker has this genotype, as ALT is often used as an indicator of liver health and Walker is likely to have a lower than average resting ALT activity. As such, an increase in Walker’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Collie Eye Anomaly (NHEJ1)

Identified in Lancashire Heelers

Primary Lens Luxation (ADAMTS17)

Identified in Lancashire Heelers

Craniomandibular Osteopathy, CMO (SLC37A2)

Identified in Lancashire Heelers

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

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Other Body Features

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Body Size

Performance

Performance

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Through Walker’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Mashury Feel It In My Soul’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Mashury Feel It In My Soul’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

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Through Walker’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

Hc.17

Map

A2b

Mashury Feel It In My Soul’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

Hc.17

Mashury Feel It In My Soul’s Haplotype

Part of the A2b haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

A2b is found in the Daschund breed.

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