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“Amaroq”
Vokterhund Nothing Is Hidden

Central Asian Shepherd Dog

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Genetic Breed Result

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Central Asian Shepherd Dog

The Central Asian Shepherd Dog is a large, powerful breed that originates from, well, Central Asia! They are an ancient breed that hails from modern day countries like Kazakstan, Afghanistan, and Tadzhikistan. They were bred over the course of thousands of years to be an excellent guardian of livestock—usually sheep—and a faithful companion to their owner. While the Central Asian Sheepdog’s bloodline can be traced over a thousand years, they weren’t commercially bred in kennels until the 20th century in the former USSR.

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Health Summary

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Amaroq has one variant that you should let your vet know about.

ALT Activity

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Amaroq inherited one copy of the variant we tested

Why is this important to your vet?

Amaroq has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Amaroq has this genotype, as ALT is often used as an indicator of liver health and Amaroq is likely to have a lower than average resting ALT activity. As such, an increase in Amaroq’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Dystrophic Epidermolysis Bullosa (COL7A1, Central Asian Shepherd Dog Variant)

Identified in Central Asian Shepherd Dogs

Additional Genetic Conditions

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Through Amaroq’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A512

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A1d

Vokterhund Nothing Is Hidden’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A512

Vokterhund Nothing Is Hidden’s Haplotype

Part of the A1d haplogroup, the A512 haplotype occurs most commonly in mixed-breed dogs.

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

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Through Amaroq’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H7.5

Map

D

Vokterhund Nothing Is Hidden’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H7.5

Vokterhund Nothing Is Hidden’s Haplotype

Part of the D haplogroup, the H7.5 haplotype occurs most commonly in Lhasa Apsos. We've also spotted it in Southeast Asian Village Dogs and East Asian Village Dogs.

Some other Embark dogs with this haplotype:

The D paternal lineage is common in Boxers.

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