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“Secret”
CH Vestavia Talking in Your Sleep TKN DCAT CAA

Cardigan Welsh Corgi

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Place of Birth

USA

Current Location

USA

From

USA

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Registration

American Kennel Club (AKC): DN61948206
Microchip: 956000012363168

Genetic Breed Result

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Cardigan Welsh Corgi

Though less common than their Pembroke cousins, the Cardigan Welsh Corgi is perfectly suited to move cattle, as well as be a smart, driven companion for the right people. This breed is highly trainable, and often compared to a German Shepherd Dog in drive and attitude. Cardigans have the bark of a much bigger dog!

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Changes to this dog’s profile
  • On 7/10/2020 changed name from "Vestavia's Talking in Your Sleep" to "Vestavia Talking in Your Sleep"
  • On 5/26/2020 changed name from "Vestavia's" to "Vestavia's Talking in Your Sleep"

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Health Summary

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Secret is at increased risk for one genetic health condition.

Intervertebral Disc Disease (Type I)

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Secret inherited both copies of the variant we tested

How to interpret this result

Secret has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Cardigan Welsh Corgis

X-linked Severe Combined Immunodeficiency, X-SCID (IL2RG, Corgi Variant)

Identified in Cardigan Welsh Corgis

Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Cardigan Welsh Corgis

Degenerative Myelopathy, DM (SOD1A)

Identified in Cardigan Welsh Corgis

Exercise-Induced Collapse, EIC (DNM1)

Identified in Cardigan Welsh Corgis

Additional Genetic Conditions

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Through Secret’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A263

Map

A1a

Vestavia Talking in Your Sleep’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A263

Vestavia Talking in Your Sleep’s Haplotype

Part of the large A1a haplogroup, we see this haplotype most frequently in Cardigan Welsh Corgis and Pembroke Welsh Corgis.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Secret inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Secret is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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