“Zhanna”
Valiant Vanessa Verdi For Joy

Shih Tzu

No bio has been provided yet

Current Location
Delta, Colorado, USA

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Genetic Breed Result

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Shih Tzu

Shih Tzu Shih Tzu
This ancient breed is the perfect lapdog. Sweet and easygoing, they want nothing more than to be close to their humans.
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Genetic Stats


Predicted Adult Weight
Genetic Age
42 human years Learn More
Based on the date of birth provided
Changes to this dog’s profile
Learn More
  • On 11/9/2020 changed name from "Valiant Vanessa Verdi For Odessa Joy" to "Valiant Vanessa Verdi For Joy"

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Health Summary

Zhanna inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

Zhanna inherited one copy of the variant we tested

What does this result mean?

This result should not impact Zhanna’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

This result should be taken into account as part of your breeding program. Zhanna will pass this variant to ~50% of her offspring.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.


ALT Activity

Zhanna inherited one copy of the variant we tested

Why is this important to your vet?

Zhanna has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Zhanna has this genotype, as ALT is often used as an indicator of liver health and Zhanna is likely to have a lower than average resting ALT activity. As such, an increase in Zhanna’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Prekallikrein Deficiency (KLKB1 Exon 8)

Identified in Shih Tzus

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Shih Tzus

Additional Genetic Conditions

Explore the genetics behind your dog’s appearance and size.
Coat Color

Coat Color

E Locus (MC1R)
Can have a melanistic mask (EmEm)
K Locus (CBD103)
More likely to have a mostly solid black or brown coat (KBKB)
Intensity Loci LINKAGE
No impact on coat pattern (Intermediate Red Pigmentation)
A Locus (ASIP)
Not expressed (ayay)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (Dd)
B Locus (TYRP1)
Black or gray hair and skin (Bb)
Saddle Tan (RALY)
Not expressed (NN)
S Locus (MITF)
Likely flash, parti, piebald, or extreme white (spsp)
M Locus (PMEL)
No merle alleles (mm)
H Locus (Harlequin)
No harlequin alleles (hh)
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely furnished (mustache, beard, and/or eyebrows) (FF)
Coat Length (FGF5)
Likely long coat (TT)
Shedding (MC5R)
Likely light shedding (CT)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Hairlessness (SGK3)
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely wavy coat (CC)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Back Muscling & Bulk, Large Breed (ACSL4)
Likely normal muscling (CC)
Body Size

Body Size

Body Size (IGF1)
Smaller (II)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Smaller (AA)
Body Size (GHR - E191K)
Smaller (AA)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)

Through Zhanna’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A4

Haplotype

A454

Map

A4

Valiant Vanessa Verdi For Joy’s Haplogroup

The A4 maternal lineage is fairly rare. It is found in Cocker Spaniels, but A4 is also represented well among East Asian breeds including the Chinese Crested Dog, Shar-Pei and Shih Tzu. Moving away from Asia, it is also found among Chihuahuas (a very old breed!) and village dogs in Peru. This may be a lineage that moved into Western breeds because of their owners' tendencies to mix them up with Eastern breeds in the early modern period.

A454

Valiant Vanessa Verdi For Joy’s Haplotype

Part of the A4 haplogroup, the A454 haplotype occurs most commonly in Shih Tzus and Chinese Shar-Peis.

Some other Embark dogs with this haplotype:

The popular Chihuahua breed descends from the A4 maternal line.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Zhanna inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Zhanna is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.