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“Kosmo”
Turkey Run Detroit vs Everybody

“Kosmo is a high energy and high drive boy who loves to play disc and herd livestock. He is very intelligent and quick to learn.”

Place of Birth

Eminence, KY, USA

Current Location

Clarkston, MI, USA

From

Eminence, KY, USA

This dog has been viewed and been given 2 wags

Registration

American Kennel Club (AKC): DN52771204

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Changes to this dog’s profile
  • On 1/13/2020 changed name from "Turkey Run Detroit vs Everybody (Kosmo)" to "Turkey Run Detroit vs Everybody"

Health Summary

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Kosmo has one variant that you should let your vet know about.

ALT Activity

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Kosmo inherited both copies of the variant we tested

Why is this important to your vet?

Kosmo has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Kosmo's ALT activity above their current, healthy, ALT activity. As an increase above Kosmo’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Australian Shepherds, Border Collies, and more

Trapped Neutrophil Syndrome, TNS (VPS13B)

Identified in Border Collies

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Australian Shepherds

Collie Eye Anomaly (NHEJ1)

Identified in Australian Shepherds, Border Collies, and more

Canine Multifocal Retinopathy, cmr1 (BEST1 Exon 2)

Identified in Australian Shepherds

Hereditary Cataracts (HSF4 Exon 9, Australian Shepherd Variant)

Identified in Australian Shepherds

Primary Lens Luxation (ADAMTS17)

Identified in Border Collies

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 SNP, Border Collie Variant)

Identified in Border Collies

Neuronal Ceroid Lipofuscinosis 6, NCL 6 (CLN6 Exon 7, Australian Shepherd Variant)

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8, Australian Shepherd Variant)

Identified in Australian Shepherds

Degenerative Myelopathy, DM (SOD1A)

Identified in Australian Shepherds and Collies

Myotonia Congenita (CLCN1 Exon 23, Australian Cattle Dog Variant)

Identified in Border Collies

Cobalamin Malabsorption (CUBN Exon 53, Border Collie Variant)

Identified in Border Collies

Craniomandibular Osteopathy, CMO (SLC37A2)

Identified in Australian Shepherds

Additional Genetic Conditions

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Traits

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Coat Color

Coat Color

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