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“Trixie”
CH Dolce Vita Joy to the World CGCA CGCU NACSW ORT

Lagotto Romagnolo

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“Trixie loves people and any activity we engage in.”

Place of Birth

Quakertown, PA, USA

Current Location

Maryland, USA

From

Quakertown, PA, USA

This dog has been viewed and been given 1 wag

Registration

American Kennel Club (AKC): SS04427004

Genetic Breed Result

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Lagotto Romagnolo

Lagotto Romagnolos are an Italian breed of dog from the Romagna region of Italy. Sporting curly hair and charming faces, they were originally bred as hunting dogs during the Medieval Period; however, today they are mostly kept as pets and as a different kind of hunting dog—Lagotto Romagnolos are expert truffle dogs. Their wonderful sense of smell makes them a great candidate for finding and unearthing truffles, rare and expensive mushrooms that are considered culinary delicacies.

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Genetic Stats

Predicted Adult Weight

26 lbs

Genetic Age
38 human years

Based on the date of birth provided

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Changes to this dog’s profile
  • On 4/22/2021 changed name from "CH Dolce Vita Joy to the World CGCA CGCU NACSW ORT" to "CH Dolce Vita Joy to the World"
  • On 4/22/2021 changed name from "CH Dolce Vita Joy to the World" to "CH Dolce Vita Joy to the World CGCA CGCU NACSW ORT"
  • On 4/22/2021 changed name from "CH Dolce Vita Joy to the World CGCA CGCU NACSW ORT" to "CH Dolce Vita Joy to the World"
  • On 4/22/2021 changed name from "Trixie" to "CH Dolce Vita Joy to the World CGCA CGCU NACSW ORT"

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Health Summary

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Trixie inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, crd4/cord1

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Trixie inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Trixie is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

ALT Activity

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Trixie inherited both copies of the variant we tested

Why is this important to your vet?

Trixie has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Trixie's ALT activity above their current, healthy, ALT activity. As an increase above Trixie’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Urate Kidney & Bladder Stones (SLC2A9)

Identified in Lagotto Romagnolos

Lagotto Storage Disease (ATG4D)

Identified in Lagotto Romagnolos

Juvenile Epilepsy (LGI2)

Identified in Lagotto Romagnolos

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Trixie’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

CH Dolce Vita Joy to the World’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

CH Dolce Vita Joy to the World’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Trixie inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Trixie is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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