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“Mini Carmelita”
TLS Mini S’mores

Bulldog

“Chocolate Merle Seal wiggle butt... loves toys”

Instagram tag
@tlsexotic.breeds.only

Place of Birth

Greensboro, NC, USA

Current Location

Raleigh, NC, USA

From

Raleigh, NC, USA

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Registration

American Kennel Club (AKC):

Genetic Breed Result

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Bulldog

Originally a bull-baiting dog, bulldogs today are gentle and loving while still carrying the stocky frame of their forbearers.

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Health Summary

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Mini Carmelita inherited one variant that you should learn more about.

Urate Kidney & Bladder Stones

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Mini Carmelita inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Mini Carmelita’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Mini Carmelita is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

Breed-Relevant Genetic Conditions

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Canine Multifocal Retinopathy, cmr1 (BEST1 Exon 2)

Identified in Bulldogs

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Mini Carmelita’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A542

Map

A1d

TLS Mini S’mores’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A542

TLS Mini S’mores’s Haplotype

Part of the A1d haplogroup, the A542 haplotype occurs most commonly in Bulldogs. It's a rare find!

The vast majority of Rottweilers have the A1d haplogroup.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Mini Carmelita inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Mini Carmelita is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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