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Tiptoe

Mixed Ancestry

“As a baby, Tiptoe could saw a bra down the middle. She regularly hid bisected bra cups around the house to pull out as needed to nap on location. Tiptoe is the sweetest, most innocent soul. She's endlessly patient with tiny puppies. She met her first mud puddle last year & fell in love! She adores her human and doggo friends & family so much I have to reign her in if a dog tries to be aggressive with any of the above. Tiptoe loves her ball and sunbathing and watching the world for hours ❤️️”

Place of Birth

Greensboro, North Carolina, USA

Current Location

Chapel Hill, North Carolina, USA

From

Greensboro, North Carolina, USA

This dog has been viewed and been given 80 wags

Genetic Breed Result

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Great Pyrenees

The Great Pyrenees is an exceptionally loving dog whose primary function is to protect sheep, goats, livestock, people, children, grass, flowers, the moon, lawn furniture, etc., from any real or imaginary predators that may intrude on your personal space. They have a strong build and an amazing thick white coat that exudes elegance and majesty. They make a great family dog because of their intelligence and steady temperament.

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American Staffordshire Terrier

American Staffordshire Terriers are powerful but playful dogs that are both loyal and affectionate with their owners.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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American Foxhound

American Foxhounds, the American cousin of the English Foxhounds, are a lucky breed because their history and ancestry are well documented. They came over to the New World in 1650 with a man named Robert Brooke, who sailed from England to Crown Colony in North America (now modern day Maryland and Virginia). This pack of hunting dogs, beloved by the Brooke Family for hundreds of years, evolved to become the American Foxhound. The Brooke hounds were likely mixed with French hounds that were also brought to the Americas, and it was this mix of European breeds that eventually gave us our beloved American Foxhound.

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Dogs Like Tiptoe

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Discover dogs who share a similar breed mix to Tiptoe. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
American Pit Bull Terrier
Great Pyrenees
American Staffordshire Terrier
Boxer
American Foxhound

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Here’s what Tiptoe’s family tree may have looked like.
Tiptoe
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed American Pit Bull Terrier mix American Pit Bull Terrier / Boxer mix Great Pyrenees / American Foxhound mix American Pit Bull Terrier American Staffordshire Terrier / American Pit Bull Terrier mix American Pit Bull Terrier Boxer Great Pyrenees American Foxhound mix American Pit Bull Terrier American Pit Bull Terrier American Staffordshire Terrier American Pit Bull Terrier
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Tiptoe’s breed mix.

Breed Reveal Video

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Health Summary

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Tiptoe inherited two variants that you should learn more about.

Urate Kidney & Bladder Stones

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Tiptoe inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Tiptoe’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Tiptoe is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

Degenerative Myelopathy, DM

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Tiptoe inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Tiptoe’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Tiptoe is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency

Identified in American Foxhounds

Hemophilia A

Identified in Boxers

Glanzmann's Thrombasthenia Type I

Identified in Great Pyrenees

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers and American Staffordshire Terriers

Canine Multifocal Retinopathy, cmr1

Identified in Great Pyrenees

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers and American Staffordshire Terriers

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers and American Staffordshire Terriers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Tiptoe’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A4

Haplotype

A454

Map

A4

Tiptoe’s Haplogroup

The A4 maternal lineage is fairly rare. It is found in Cocker Spaniels, but A4 is also represented well among East Asian breeds including the Chinese Crested Dog, Shar-Pei and Shih Tzu. Moving away from Asia, it is also found among Chihuahuas (a very old breed!) and village dogs in Peru. This may be a lineage that moved into Western breeds because of their owners' tendencies to mix them up with Eastern breeds in the early modern period.

A454

Tiptoe’s Haplotype

Part of the A4 haplogroup, the A454 haplotype occurs most commonly in Shih Tzus and Chinese Shar-Peis.

The popular Chihuahua breed descends from the A4 maternal line.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Tiptoe inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Tiptoe is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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