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Tillie

“Tillie”
Tillie

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Genetic Stats


Predicted Adult Weight

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Health Summary

Tillie has one variant that you should let your vet know about.

ALT Activity

Tillie inherited one copy of the variant we tested

Why is this important to your vet?

Tillie has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Tillie has this genotype, as ALT is often used as an indicator of liver health and Tillie is likely to have a lower than average resting ALT activity. As such, an increase in Tillie’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Von Willebrand Disease Type I (VWF)

Identified in Standard Poodles

Canine Elliptocytosis (SPTB Exon 30)

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency (PKLR Exon 7 Labrador Variant)

Identified in Labrador Retrievers

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Labrador Retrievers and Standard Poodles

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2 (TTC8)

Identified in Labrador Retrievers

Progressive Retinal Atrophy - crd4/cord1 (RPGRIP1)

Identified in Labrador Retrievers

Day Blindness (CNGA3 Exon 7 Labrador Retriever Variant)

Identified in Labrador Retrievers

Macular Corneal Dystrophy, MCD (CHST6)

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Labrador Retrievers

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles

Alexander Disease (GFAP)

Identified in Labrador Retrievers

Degenerative Myelopathy, DM (SOD1A)

Identified in Standard Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles

Narcolepsy (HCRTR2 Intron 6)

Identified in Labrador Retrievers

Centronuclear Myopathy (PTPLA)

Identified in Labrador Retrievers

Exercise-Induced Collapse (DNM1)

Identified in Labrador Retrievers

X-Linked Myotubular Myopathy (MTM1, Labrador Variant)

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome (COLQ)

Identified in Labrador Retrievers

Hereditary Nasal Parakeratosis (SUV39H2)

Identified in Labrador Retrievers

Osteochondrodysplasia (SLC13A1)

Identified in Standard Poodles

Skeletal Dysplasia 2, SD2 (COL11A2)

Identified in Labrador Retrievers

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Standard Poodles

Additional Genetic Conditions

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