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Thorin

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“Thorin is a 1st generation Tamaskan. His father is Midas from Sweden. Thorin is very sweet and curious. Can be timid with men at first, but is happy if you're willing to play. He's a very quick learner and impresses me with his ability to generalize.”

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@ThorinTheTamaskan

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Health Summary

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Thorin has one variant that you should let your vet know about.

ALT Activity

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Thorin inherited one copy of the variant we tested

Why is this important to your vet?

Thorin has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Thorin has this genotype, as ALT is often used as an indicator of liver health and Thorin is likely to have a lower than average resting ALT activity. As such, an increase in Thorin’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

Hemophilia A (F8 Exon 11, German Shepherd Variant 1)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

Hemophilia A (F8 Exon 1, German Shepherd Variant 2)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

Day Blindness (CNGA3 Exon 7, German Shepherd Variant)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Degenerative Myelopathy, DM (SOD1A)

Identified in Czechoslovakian Vlcaks and German Shepherd Dogs

Additional Genetic Conditions

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