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Thane

No bio has been provided yet

Place of Birth
Hamilton, Ohio, USA
Current Location
Springfield, Ohio, USA
From
Hamilton, Ohio, USA

This dog has been viewed 409 times and been given 1 wag

Genetic Breed Result

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30.9% German Shepherd Dog
25.1% Gray Wolf
20.4% Alaskan Malamute
16.1% Siberian Husky
7.5% Collie
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Genetic Stats


Wolfiness

14.4 % HIGH Learn More

Predicted Adult Weight
Genetic Age
20 human years Learn More
Based on the date of birth provided

DNA Breed Origins

What’s this?
Breed colors:
German Shepherd Dog
Gray Wolf
Alaskan Malamute
Siberian Husky
Collie

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Summary

0
AT RISK
0
CARRIER
171
CLEAR
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Clinical Traits

These clinical traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal

Thane has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Thane has this genotype, as ALT is often used as an indicator of liver health and Thane is likely to have a lower than average resting ALT activity. As such, an increase in Thane’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

Genetic Health Conditions

A genetic health condition indicates a genetic mutation that increases the risk that an animal develops a specific disease.

Not At Risk

Good news! Thane did not test positive for any of the genetic conditions that Embark screens for.

It is still important to let your veterinarian know these results because they could help guide Thane’s diagnosis and treatment if he gets sick in the future.

Not A Carrier

Good news! Thane is not a carrier for any of the genetic conditions that Embark tests for.

Common Conditions

Good news! Thane tested clear for 14 genetic conditions that are common in his breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, Collies, but not Thane.

Factor VII Deficiency
(F7 Exon 5)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in Alaskan Malamutes, but not Thane.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Thane.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Thane.

Canine Leukocyte Adhesion Deficiency Type III, LAD3
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Thane.

Collie Eye Anomaly, Choroidal Hypoplasia, CEA
(NHEJ1)
Eyes

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia and is a developmental disease of the choroid. The ch…

Seen in Collies, but not Thane.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Thane.

Hyperuricosuria and Hyperuricemia or Urolithiasis, HUU
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in German Shepherd Dogs, but not Thane.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Thane.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis, RCND
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Thane.

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Thane.

GM1 Gangliosidosis
(GLB1 Exon 15 Alaskan Husky Variant)
Multisystem

An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Seen in Siberian Huskys, but not Thane.

Degenerative Myelopathy, DM
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in German Shepherd Dogs, Collies, but not Thane.

Polyneuropathy, NDRG1 Malamute Variant
(NDRG1 Exon 4)
Brain and Spinal Cord

Polyneuropathy is a progressive neurologic disease that causes peripheral nerve dysfunction. Peripheral nerves relay messages between the brain and spinal cord to the res…

Seen in Alaskan Malamutes, but not Thane.

Other Conditions:
Clear of 157

Thane is clear of 157 other genetic conditions that Embark tests for.
Explore the genetics behind your dog’s appearance, size, and genetic diversity.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have patterned fur
Body Pattern
A (Agouti) Locus
Agouti (Wolf Sable) coat color pattern
Facial Fur Pattern
E (Extension) Locus
No dark mask or grizzle facial fur patterns
Saddle Tan
No impact on coat pattern
Merle
M (Merle) Locus
Unlikely to have merle pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Larger
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance

Through Thane’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A295

Map

A1e

Thane’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A295

Thane’s Haplotype

Part of the large A1e haplogroup, we have found this haplotype in village dogs in Afghanistan, Liberia, and Qatar. We see this haplotype most frequently in Scottish Terriers, Jack Russell Terriers, and Brussels Griffons.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

Through Thane’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1.2

Map

B1

Thane’s Haplogroup

This is a lineage that is found infrequently in dogs and may only be found in gray wolves and dogs with recent wolf ancestors. It is very different from all known dog lineages indicating a long time between the most recent common ancestor of canids in this lineage and domestic dogs.

B1.2

Thane’s Haplotype

This haplotype has been spotted in wolves and dogs with wolf ancestry. Not only is that pretty neat, but it also helps move science forward.

Some other Embark dogs with this haplotype:

The mysterious wolf hides many genetic mysteries unknown to science - like where this male lineage came from.