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Thane

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Place of Birth

Hamilton, Ohio, USA

Current Location

Springfield, Ohio, USA

From

Hamilton, Ohio, USA

This dog has been viewed and been given 2 wags

Genetic Breed Result

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Genetic Stats

Wolfiness

14.4 % HIGH

Predicted Adult Weight

74 lbs

Genetic Age
38 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
German Shepherd Dog
Gray Wolf
Alaskan Malamute
Siberian Husky
Collie

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Health Summary

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Thane has one variant that you should let your vet know about.

ALT Activity

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Thane inherited one copy of the variant we tested

Why is this important to your vet?

Thane has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Thane has this genotype, as ALT is often used as an indicator of liver health and Thane is likely to have a lower than average resting ALT activity. As such, an increase in Thane’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Collies and German Shepherd Dogs

Factor VII Deficiency

Identified in Alaskan Malamutes

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

X-Linked Progressive Retinal Atrophy 1, XL-PRA1

Identified in Siberian Huskies

Collie Eye Anomaly

Identified in Collies

Day Blindness

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones

Identified in German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

GM1 Gangliosidosis

Identified in Siberian Huskies

Degenerative Myelopathy, DM

Identified in German Shepherd Dogs

Alaskan Malamute Polyneuropathy, AMPN

Identified in Alaskan Malamutes

Additional Genetic Conditions

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Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Thane’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A295

Map

A1e

Thane’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A295

Thane’s Haplotype

Part of the large A1e haplogroup, we have found this haplotype in village dogs in Afghanistan, Liberia, and Qatar. We see this haplotype most frequently in Scottish Terriers, Jack Russell Terriers, and Brussels Griffons.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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Through Thane’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1.2

Map

B1

Thane’s Haplogroup

This is a lineage that is found infrequently in dogs and may only be found in gray wolves and dogs with recent wolf ancestors. It is very different from all known dog lineages indicating a long time between the most recent common ancestor of canids in this lineage and domestic dogs.

B1.2

Thane’s Haplotype

This haplotype has been spotted in wolves and dogs with wolf ancestry. Not only is that pretty neat, but it also helps move science forward.

Some other Embark dogs with this haplotype:

The mysterious wolf hides many genetic mysteries unknown to science - like where this male lineage came from.

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