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“Esco”
Sylvaen Hailstone

Mixed Ancestry

“He is a first generation ITR-registered Tamaskan Dog!”

Place of Birth

Drenje Brdovečko, Zagreb County, Croatia

Current Location

Luxembourg

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Registration

International Tamaskan Register (ITR): ITR-2347G1/2022
Microchip: 191100002160836

Genetic Breed Result

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Saarloos Wolfdog

Saarloos Wolfdogs are a Dutch breed of dog that are actually the result of the careful breeding of wolf/dog hybrids. In fact, they are the breed of dog that, according to a study conducted in 2015, contain the most genetic similarity to wolves.

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Czechoslovakian Vlcak

Czechoslovakian Vlcaks are a relatively new breed of dog that hail from Czechoslovakia. Nearly indistinguishable from a wolf to an untrained eye, these large and handsome dogs are the result of a crossbreeding between a German Shepherd and a Carpathian wolf in the 1950’s.

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DNA Breed Origins

Breed colors:
Siberian Husky
German Shepherd Dog
Saarloos Wolfdog
Czechoslovakian Vlcak

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Changes to this dog’s profile
  • On 10/20/2022 changed handle from "sylvaenhailstone" to "sylvaen_hailstone"

Health Summary

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Esco has one variant that you should let your vet know about.

ALT Activity

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Esco inherited one copy of the variant we tested

Why is this important to your vet?

Esco has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Esco has this genotype, as ALT is often used as an indicator of liver health and Esco is likely to have a lower than average resting ALT activity. As such, an increase in Esco’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Hemophilia A (F8 Exon 11, German Shepherd Variant 1)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Hemophilia A (F8 Exon 1, German Shepherd Variant 2)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Platelet Factor X Receptor Deficiency, Scott Syndrome (TMEM16F)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant)

Identified in Siberian Huskies

Day Blindness (CNGA3 Exon 7, German Shepherd Variant)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Degenerative Myelopathy, DM (SOD1A)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Ichthyosis (ASPRV1 Exon 2, German Shepherd Variant)

Identified in German Shepherd Dogs

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Esco’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A388

Map

A1a

Sylvaen Hailstone’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A388

Sylvaen Hailstone’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Staffordshire Terriers, Labrador Retrievers, and English Bulldogs.

Shar Pei dogs think A1a is the coolest!

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Through Esco’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A

Haplotype

Hc.1

Map

A

Sylvaen Hailstone’s Haplogroup

A is the distant relative of some of the most numerous paternal lineages in the world. Characterized by a single sub-lineage, this is a rare and interesting paternal line! The A line is found most commonly in Siberian Huskies and in Alaskan village dogs. It seems plausible that this paternal lineage diverged within the last 10,000 years from a group arriving with the first Arctic explorers. The recent ancestors of dogs with this lineage actually allowed humans to survive in some of the most forbidding conditions on the face of the earth!

Hc.1

Sylvaen Hailstone’s Haplotype

The lone member of the A haplogroup, this haplotype occurs most commonly in Siberian Huskies and village dogs from Alaska.

Siberian Huskys are the only breed to have the A haplogroup.

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