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“Sebastian”
Sylvaen Elemental Fragment

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“He is a second generation ITR-registered Tamaskan Dog!”

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Registration

International Tamaskan Register (ITR): ITR-2207G2/2021
Microchip: 191100002144378

Genetic Breed Result

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Genetic Stats

Predicted Adult Weight

74 lbs

Genetic Age
19 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
German Shepherd Dog
Siberian Husky
Gray Wolf
Alaskan Malamute
Collie

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Changes to this dog’s profile
  • On 5/15/2021 changed handle from "sylvaenelementalfragment" to "sylvaen_elemental_fragment"

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Health Summary

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Sebastian has one variant that you should let your vet know about.

ALT Activity

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Sebastian inherited one copy of the variant we tested

Why is this important to your vet?

Sebastian has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Sebastian has this genotype, as ALT is often used as an indicator of liver health and Sebastian is likely to have a lower than average resting ALT activity. As such, an increase in Sebastian’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Collies and German Shepherd Dogs

Factor VII Deficiency (F7 Exon 5)

Identified in Alaskan Malamutes

Hemophilia A (F8 Exon 11, German Shepherd Variant 1)

Identified in German Shepherd Dogs

Hemophilia A (F8 Exon 1, German Shepherd Variant 2)

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)

Identified in German Shepherd Dogs

Platelet Factor X Receptor Deficiency, Scott Syndrome (TMEM16F)

Identified in German Shepherd Dogs

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Collie Eye Anomaly (NHEJ1)

Identified in Collies

Day Blindness (CNGA3 Exon 7, German Shepherd Variant)

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in German Shepherd Dogs

Primary Ciliary Dyskinesia, PCD (NME5, Alaskan Malamute Variant)

Identified in Alaskan Malamutes

Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in German Shepherd Dogs

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Degenerative Myelopathy, DM (SOD1A)

Identified in German Shepherd Dogs

Alaskan Malamute Polyneuropathy, AMPN (NDRG1 SNP)

Identified in Alaskan Malamutes

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Sebastian’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A388

Map

A1a

Sylvaen Elemental Fragment’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A388

Sylvaen Elemental Fragment’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Staffordshire Terriers, Labrador Retrievers, and English Bulldogs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Through Sebastian’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.15

Map

A1a

Sylvaen Elemental Fragment’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.15

Sylvaen Elemental Fragment’s Haplotype

Part of the large A1a haplogroup, this haplotype is found in village dogs from across the globe (outside of Asia). As for breeds, it is primarily seen in German Shepherds, Labrador Retrievers, Nova Scotia Duck Tolling Retriever. It is by far the most common haplotype in German Shepherds.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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