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“Maddox”
Sylvaen Bothan

Mixed Ancestry

“He is a second generation ITR-registered Tamaskan Dog!”

Place of Birth

Drenje Brdovečko, Zagreb County, Croatia

Current Location

Canada

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Registration

International Tamaskan Register (ITR): ITR-2359G2/2022
Microchip: 191100002161296

Genetic Breed Result

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Czechoslovakian Vlcak

Czechoslovakian Vlcaks are a relatively new breed of dog that hail from Czechoslovakia. Nearly indistinguishable from a wolf to an untrained eye, these large and handsome dogs are the result of a crossbreeding between a German Shepherd and a Carpathian wolf in the 1950’s.

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Belgian Sheepdog

The Belgian Sheepdog is one of the four varieties of Belgian Shepherd, though the AKC distinguishes them as their own breed. This active working dog is renowned for its intelligence and drive. If given the opportunity for plenty of physical and mental exercise, the Belgian Sheepdog will astound you with its athleticism and versatility.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Saarloos Wolfdog

Saarloos Wolfdogs are a Dutch breed of dog that are actually the result of the careful breeding of wolf/dog hybrids. In fact, they are the breed of dog that, according to a study conducted in 2015, contain the most genetic similarity to wolves.

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Belgian Tervuren

The Belgian Tervuren is one of the four varieties of Belgian Shepherd, though the AKC distinguishes them as their own breed. This active working dog is renowned for its intelligence and drive. If given the opportunity for plenty of physical and mental exercise, the Belgian Tervuren will astound you with its athleticism and versatility.

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DNA Breed Origins

Breed colors:
Siberian Husky
Czechoslovakian Vlcak
Belgian Sheepdog
German Shepherd Dog
Saarloos Wolfdog
Belgian Tervuren

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Changes to this dog’s profile
  • On 11/2/2022 changed handle from "sylvaenbothan" to "sylvaen_bothan"

Health Summary

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Maddox has one variant that you should let your vet know about.

ALT Activity

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Maddox inherited one copy of the variant we tested

Why is this important to your vet?

Maddox has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Maddox has this genotype, as ALT is often used as an indicator of liver health and Maddox is likely to have a lower than average resting ALT activity. As such, an increase in Maddox’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Hemophilia A (F8 Exon 11, German Shepherd Variant 1)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Hemophilia A (F8 Exon 1, German Shepherd Variant 2)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Platelet Factor X Receptor Deficiency, Scott Syndrome (TMEM16F)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant)

Identified in Siberian Huskies

Day Blindness (CNGA3 Exon 7, German Shepherd Variant)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in Belgian Sheepdogs, Belgian Tervurens, and more

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Degenerative Myelopathy, DM (SOD1A)

Identified in Czechoslovakian Vlcaks, German Shepherd Dogs, and more

Spongy Degeneration with Cerebellar Ataxia 1 (KCNJ10)

Identified in Belgian Sheepdogs and Belgian Tervurens

Spongy Degeneration with Cerebellar Ataxia 2 (ATP1B2)

Identified in Belgian Sheepdogs and Belgian Tervurens

Cardiomyopathy and Juvenile Mortality (YARS2)

Identified in Belgian Sheepdogs and Belgian Tervurens

Ichthyosis (ASPRV1 Exon 2, German Shepherd Variant)

Identified in German Shepherd Dogs

Additional Genetic Conditions

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Traits

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

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Body Size

Body Size

Performance

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Through Maddox’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A388

Map

A1a

Sylvaen Bothan’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A388

Sylvaen Bothan’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Staffordshire Terriers, Labrador Retrievers, and English Bulldogs.

Shar Pei dogs think A1a is the coolest!

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Through Maddox’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.15

Map

A1a

Sylvaen Bothan’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.15

Sylvaen Bothan’s Haplotype

Part of the large A1a haplogroup, this haplotype is found in village dogs from across the globe (outside of Asia). As for breeds, it is primarily seen in German Shepherds, Labrador Retrievers, Nova Scotia Duck Tolling Retriever. It is by far the most common haplotype in German Shepherds.

Dogs with A1a lineage travelled during European Colonial times.

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