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Sweety

Beagle (5.5% unresolved)

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“Sweety loves to be held. She LOVES to play ball, walk. She is very calm unless someone new comes around or if she is playing ball. She goes INSANE for a ball. At bedtime I have to cover Sweety with a blanket before she will go to sleep.. She also has random seizures and we do not know why this occurs . I hope this kit gives us some kind of insight.”

Current Location

South Carolina, USA

This dog has been viewed and been given 44 wags

Genetic Breed Result

Sweety

Sweety

Beagle (5.5% unresolved)
94.5% Beagle

Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from this distant ancestor:

Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Genetic Stats

Wolfiness

0.6 % LOW

Predicted Adult Weight

31 lbs

Genetic Age
69 human years

Based on the date of birth provided

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Sweety
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Beagle mix Beagle Beagle Beagle mix Beagle Beagle Beagle Beagle Beagle Beagle mix Beagle Beagle Beagle Beagle

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Sweety’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Sweety is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Sweety inherited one copy of the variant we tested

How to interpret this result

Sweety has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Musladin-Lueke Syndrome, MLS

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Sweety inherited one copy of the variant we tested

What does this result mean?

This result does not impact your dog’s health. It could have consequences for siblings or other family members, and you should let them know if you are in contact with them.

What is Musladin-Lueke Syndrome, MLS?

This condition causes abnormally strong connections between the structural proteins that provide strength and integrity to tissues like the skin and skeletal muscle, as well as the protective tissue sheaths of the bones and central nervous system.

ALT Activity

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Sweety inherited one copy of the variant we tested

Why is this important to your vet?

Sweety has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Sweety has this genotype, as ALT is often used as an indicator of liver health and Sweety is likely to have a lower than average resting ALT activity. As such, an increase in Sweety’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency

Identified in Beagles

Pyruvate Kinase Deficiency

Identified in Beagles

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles

Primary Open Angle Glaucoma

Identified in Beagles

Congenital Stationary Night Blindness

Identified in Beagles

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Light colored fur (cream to red)
Dark brown pigment
Cocoa
No impact on skin color
Red Pigment Intensity LINKAGE
I (Intensity) Loci
Any pigmented fur likely yellow or tan
Brown or Black Pigment
B (Brown) Locus
Likely black colored nose/feet
Color Dilution
D (Dilute) Locus
Dark (non-dilute) skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
No impact on coat color
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
No dark fur anywhere
Saddle Tan
No impact on coat pattern
White Spotting
S (White Spotting) Locus
Likely to have large white areas in coat
Roan LINKAGE
R (Roan) Locus
Likely no impact on coat pattern
Merle
M (Merle) Locus
No impact on coat color
Harlequin
No impact on coat pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Smaller
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Intermediate
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation
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Through Sweety’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A425

Map

A1d

Sweety’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A425

Sweety’s Haplotype

Part of the A1d haplogroup, the A425 haplotype occurs most commonly in Greater Swiss Mountain Dogs. It's a rare find!

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Sweety inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Sweety is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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