“Sunny”
Mountain Top You Are May Sunshine ☀️

Beagle

“loves to hunt !!! Small in size”

Place of Birth
Viper, Kentucky, USA
Current Location
Viper, Kentucky, USA
From
Viper, Kentucky, USA

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Registration

Mountain Top: EM-1518885

Genetic Breed Result

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Beagle

Beagle Beagle
The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.
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Genetic Stats


Predicted Adult Weight
Genetic Age
21 human years Learn More
Based on the date of birth provided
Changes to this dog’s profile
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  • On 3/9/2020 changed name from "Sunny" to "Mountain Top You Are May Sunshine ☀️"

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Health Summary

Sunny is at increased risk for one genetic health condition.

And inherited three variants that you should learn more about.

Intervertebral Disc Disease (Type I)

Sunny inherited both copies of the variant we tested

How to interpret this result

Sunny has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Progressive Retinal Atrophy - crd4/cord1

Sunny inherited one copy of the variant we tested

What does this result mean?

This result should not impact Sunny’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring.

What is Progressive Retinal Atrophy - crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.


Hypocatalasia, Acatalasemia

Sunny inherited one copy of the variant we tested

What does this result mean?

This result should not impact Sunny’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring.

What is Hypocatalasia, Acatalasemia?

Catalase is important in fighting reactive oxygen species, which can cause cellular damage. Fortunately, many enzymes can break down reactive oxygen species; as such acatalasemia is usually a benign disease: however, some acatalasemic dogs suffer from what is known as Takahara’s disease, where patients have progressive mouth ulcers.


ALT Activity

Sunny inherited one copy of the variant we tested

Why is this important to your vet?

Sunny has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Sunny has this genotype, as ALT is often used as an indicator of liver health and Sunny is likely to have a lower than average resting ALT activity. As such, an increase in Sunny’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Factor VII Deficiency (F7 Exon 5)

Identified in Beagles

Pyruvate Kinase Deficiency (PKLR Exon 7 Beagle Variant)

Identified in Beagles

Glaucoma (ADAMTS10 Exon 17)

Identified in Beagles

Neonatal Cerebellar Cortical Degeneration (SPTBN2)

Identified in Beagles

Cobalamin Malabsorption (CUBN Exon 8)

Identified in Beagles

Musladin-Lueke Syndrome (ADAMTSL2)

Identified in Beagles

Osteogenesis Imperfecta (COL1A2)

Identified in Beagles

Additional Genetic Conditions

Explore the genetics behind your dog’s appearance and size.
Coat Color

Coat Color

E Locus (MC1R)
No dark hairs anywhere (ee)
K Locus (CBD103)
Not expressed (kyky)
Intensity Loci LINKAGE
Any pigmented hair likely yellow or tan (Intermediate Red Pigmentation)
A Locus (ASIP)
Not expressed (atat)
D Locus (MLPH)
Not expressed (DD)
B Locus (TYRP1)
Likely black colored nose/feet (Bb)
Saddle Tan (RALY)
Not expressed (NN)
S Locus (MITF)
Likely flash, parti, piebald, or extreme white (spsp)
M Locus (PMEL)
No merle alleles (mm)
H Locus (Harlequin)
No harlequin alleles (hh)
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely short or mid-length coat (GG)
Shedding (MC5R)
Likely heavy/seasonal shedding (CC)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Hairlessness (SGK3)
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely straight coat (CC)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Back Muscling & Bulk, Large Breed (ACSL4)
Likely normal muscling (CC)
Body Size

Body Size

Body Size (IGF1)
Smaller (II)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Larger (TT)
Body Size (GHR - E191K)
Intermediate (GA)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)

Through Sunny’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B92/93

Map

B1

Mountain Top You Are May Sunshine ☀️’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B92/93

Mountain Top You Are May Sunshine ☀️’s Haplotype

Part of the B1 haplogroup, the B92/93 haplotype occurs most commonly in Doberman Pinschers, West Highland White Terriers and American Pit Bull Terriers.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Sunny inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Sunny is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.