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Steph

Mixed Ancestry

“She was rescued from kill shelter in Alabama and transported to CT where we adopted her from tails of courage (which has since closed down). All we knew was that she was a Beagle-Mix and about 8 weeks old. She had 8 puppies in her litter, but she picked us. Would love to connect with the CT families that adopted her siblings! Instagram: @steph_da_pup”

Instagram tag
@steph_da_pup

Place of Birth

Alabama, USA

Current Location

Greenwich, Connecticut, USA

This dog has been viewed and been given 1 wag

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Rat Terrier

The Rat Terrier is an American dog breed with a background as a farm dog and hunting companion.

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Miniature Pinscher

The Miniature Pinscher is a small breed of dog originating from Germany. The breed's earliest ancestors may have included the German Pinscher mixed with Italian greyhounds and dachshunds.

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Shih Tzu

This ancient breed is the perfect lapdog. Sweet and easygoing, they want nothing more than to be close to their humans.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Dogs Like Steph

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Discover dogs who share a similar breed mix to Steph. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
German Shepherd Dog
Rat Terrier
Miniature Pinscher
American Pit Bull Terrier
Shih Tzu
Labrador Retriever
Beagle
Supermutt

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Here’s what Steph’s family tree may have looked like.
Steph
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed German Shepherd Dog mix Miniature Pinscher / Shih Tzu mix American Pit Bull Terrier / Beagle mix German Shepherd Dog Rat Terrier / Labrador Retriever mix Miniature Pinscher Shih Tzu mix American Pit Bull Terrier Beagle mix German Shepherd Dog German Shepherd Dog Rat Terrier Labrador Retriever mix
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Steph’s breed mix.
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Health Summary

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Steph is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Steph inherited one copy of the variant we tested

How to interpret this result

Steph has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Steph inherited one copy of the variant we tested

Why is this important to your vet?

Steph has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Steph has this genotype, as ALT is often used as an indicator of liver health and Steph is likely to have a lower than average resting ALT activity. As such, an increase in Steph’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Factor VII Deficiency

Identified in Beagles

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Canine Elliptocytosis

Identified in Labrador Retrievers

Prekallikrein Deficiency

Identified in Shih Tzus

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Beagles

Progressive Retinal Atrophy, prcd

Identified in Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd2

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles and Labrador Retrievers

Day Blindness

Identified in German Shepherd Dogs

Day Blindness

Identified in Labrador Retrievers

Primary Open Angle Glaucoma

Identified in Beagles

Primary Lens Luxation

Identified in Rat Terriers

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Cystinuria Type II-B

Identified in Miniature Pinschers

Urate Kidney & Bladder Stones

Identified in American Pit Bull Terriers, German Shepherd Dogs, and more

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

Alexander Disease

Identified in Labrador Retrievers

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Degenerative Myelopathy, DM

Identified in German Shepherd Dogs and Labrador Retrievers

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Narcolepsy

Identified in Labrador Retrievers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Labrador Retrievers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Steph’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C1

Haplotype

C39

Map

C1

Steph’s Haplogroup

Congratulations, C1 is a very exotic female lineage! It is more closely associated with maternal lineages found in wolves, foxes and jackals than with other dog lineages. So it seems dogs in this group have a common male dog ancestor who, many thousands of years ago, mated with a female wolf! This is not a common lineage in any breed, though a good number of German Shepherds and Doberman Pinchers are C1. It is also found in breeds as diverse as Peruvian Inca Orchids and Pekingese; it is rarely found amongst Labrador Retrievers, Border Collies, Siberian Huskies, or Cocker Spaniels. Despite its fascinating origins, it is widely distributed around the globe, and even shows up frequently among Peruvian village dogs. It almost certainly survived at low frequency in Europe for millennia and then was dispersed outside of Europe by colonialism, though not as successfully as some other lineages.

C39

Steph’s Haplotype

Part of the C1 haplogroup, this haplotype occurs most frequently in Pomerianians and Xoloitzcuintli.

The C1 maternal line is commonly found in Jackals.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Steph inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Steph is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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