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“Stanley”
Stanley Ipkiss von Boss

Mixed Ancestry

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“Stanley loves to eat. He is super smart and loves to go hiking and camping.”

Place of Birth

DireWolf Dogs of Vallecito, LLC, Washington 25, Fruitland, WA, USA

Current Location

DireWolf Dogs of Vallecito, LLC, Washington 25, Fruitland, WA, USA

From

DireWolf Dogs of Vallecito, LLC, Washington 25, Fruitland, WA, USA

This dog has been viewed and been given 14 wags

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Alaskan Malamute

The Alaskan Malamute is a large, fluffy spitz breed recognized as being one of the most ancient breeds of dogs. The forebears to the modern Malamute crossed the Bering Strait with their owners over 4,000 years ago. Their size, thick coat, and work drive make them ideal dogs for pulling sleds, but they also make amicable companions.

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Irish Wolfhound

The Irish Wolfhound is about as big as they come. These gentle giants have served as hunting dogs for thousands of years. They make wonderful companions, especially for kids.

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Akita

The Akita is a large breed of dog originating from the mountainous northern regions of Japan.

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Genetic Stats

Predicted Adult Weight

97 lbs

Genetic Age
47 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
German Shepherd Dog
Alaskan Malamute
Irish Wolfhound
Akita
Unresolved

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Changes to this dog’s profile
  • On 5/17/2018 changed handle from "stanleyipkissvonboss" to "stanley_ipkiss"

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Health Summary

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Stanley inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Canine Multifocal Retinopathy, cmr1

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Stanley inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Stanley is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Canine Multifocal Retinopathy, cmr1?

This is a non-progressive retinal disease that, in rare cases, can lead to vision loss. Dogs with larger lesions can suffer from vision loss. CMR is fairly non-progressive; new lesions will typically stop forming by the time a dog is an adult, and some lesions will even regress with time.

ALT Activity

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Stanley inherited both copies of the variant we tested

Why is this important to your vet?

Stanley has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Stanley's ALT activity above their current, healthy, ALT activity. As an increase above Stanley’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in German Shepherd Dogs

Factor VII Deficiency (F7 Exon 5)

Identified in Alaskan Malamutes

Hemophilia A (F8 Exon 11, German Shepherd Variant 1)

Identified in German Shepherd Dogs

Hemophilia A (F8 Exon 1, German Shepherd Variant 2)

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)

Identified in German Shepherd Dogs

Day Blindness (CNGA3 Exon 7, German Shepherd Variant)

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in German Shepherd Dogs

Degenerative Myelopathy, DM (SOD1A)

Identified in German Shepherd Dogs

Alaskan Malamute Polyneuropathy, AMPN (NDRG1 SNP)

Identified in Alaskan Malamutes

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Stanley’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Stanley Ipkiss von Boss’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Stanley Ipkiss von Boss’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Through Stanley’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C

Haplotype

H5a

Map

C

Stanley Ipkiss von Boss’s Haplogroup

C is a relatively rare paternal lineage. The dog populations which bear C are a disparate bunch. The Akita and Shiba Inu are Japanese breeds, the former of which seems to have roots in the Jomon population of hunter-gatherers which were present in the islands of Japan before the ancestors of the modern Japanese arrived. The New Guinea Singing Dog, Samoyed, and Alaska Malamute are all disparate breeds that also represent the C lineage. One village dog from Peru also bore this lineage. This wide distribution and diversity suggest C is not a recently expanded lineage. It likely represents a canid lineage which diversified sometime around the Last Glacial Maximum, when the dogs of Siberia and Oceania split off and went their separate ways.

H5a

Stanley Ipkiss von Boss’s Haplotype

Part of the C haplogroup, this haplotype occurs most commonly in Akitas and Alaskan Malamutes.

Some other Embark dogs with this haplotype:

The Shiba Inu descends from this relativey rare haplogroup.

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