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“Sprite”
Spritz Del Viale Dei Platani

Bolognese

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Place of Birth

Italy

Current Location

Illinois, USA

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Registration

Fédération Cynologique Internationale (FCI): ROI 22/131061

Genetic Breed Result

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Bolognese

The Bolognese is a small, fluffy breed who can make the ideal companion for many families. In fact, they've been bred for companionship for centuries, and were a favorited breed of Italian nobility, occasionally being given as gifts. The Bolognese is related to other dogs in the Bichon family, and are quite rare in the United States.

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Health Summary

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Sprite is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Sprite inherited one copy of the variant we tested

What does this result mean?

Follow-up by our experts indicates that this genetic variant is associated with an increase to Sprite’s risk for developing Intervertebral Disc Disease (Type I).

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to Sprite have not yet been the focus of research studies, our data indicates that Sprite is likely to be at increased risk.

Impact on Breeding

While further investigation is warranted to determine the clinical presentation and penetrance in Sprite’s breed, we recommend taking this genetic result into account when making breeding decisions.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Sprite inherited one copy of the variant we tested

Why is this important to your vet?

Sprite has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Sprite has this genotype, as ALT is often used as an indicator of liver health and Sprite is likely to have a lower than average resting ALT activity. As such, an increase in Sprite’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Sprite’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B77/B81

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B1

Spritz Del Viale Dei Platani’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B77/B81

Spritz Del Viale Dei Platani’s Haplotype

Part of the B1 haplogroup, the B77/B81 haplotype occurs most frequently in Shih Tzus, Small Poodles, and American Bullies.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Sprite’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H7.1/6/7

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D

Spritz Del Viale Dei Platani’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H7.1/6/7

Spritz Del Viale Dei Platani’s Haplotype

Part of the D haplogroup, this haplotype occurs most frequently in mixed breed dogs.

The D paternal lineage is common in Boxers.

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