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“Sose”
T'Aguhu Uzh Sose of Parik's Karvachar

Armenian Gampr

“Sose is fom Karvachar. Her mother and litter were saved during the war on Artsakh”

Instagram tag
@tribblehillfarmgamprs

Place of Birth

Current Location

Greenwood Springs, MS, USA

From

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Registration

Armenian Gampr Club of America (AGCA): 083120-01

Genetic Breed Result

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Armenian Gampr

The Armenian Gampr is an ancient, working livestock guardian dog originally bred in the southern Caucasus Mountains. The Gampr is considered a landrace rather than a breed with a closed population; they are genetically diverse with an emphasis on function rather than form. There are several regional variants of the Gampr.

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Changes to this dog’s profile
  • On 5/12/2021 changed name from "Sose" to "T'Aguhu Uzh Sose of Parik's Karvachar"

Health Summary

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Sose inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Sose inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Sose’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Sose is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Sose inherited both copies of the variant we tested

Why is this important to your vet?

Sose has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Sose's ALT activity above their current, healthy, ALT activity. As an increase above Sose’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

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Body Size

Performance

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Through Sose’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1c

Haplotype

A298

Map

A1c

T'Aguhu Uzh Sose of Parik's Karvachar’s Haplogroup

About 15,000 years ago in Central Asia, females from this lineage were some of the wolves domesticated as the original dogs. Since then, dogs from this lineage traveled through the Middle East to Africa, where they became some of the African village dogs and basenjis, which are a native African breed of dog. There are also still pockets of dogs with this lineage that remained in Asia or places along the route to Africa, such as India. This lineage has also been found in the Borzoi, a Russian dog breed.

A298

T'Aguhu Uzh Sose of Parik's Karvachar’s Haplotype

Part of the large A1c haplogroup, this haplotype occurs in village dogs in central and southern Asia (Mongolia and India, specifically).

The presence of A1c in a Borzoi indicates a deep history of this lineage in Eurasia

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Sose inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Sose is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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