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“Sora”
Corvus As the Crow Flies

Alaskan Malamute

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Place of Birth

Oregon, USA

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Registration

American Kennel Club (AKC):

Genetic Breed Result

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Alaskan Malamute

The Alaskan Malamute is a large, fluffy spitz breed recognized as being one of the most ancient breeds of dogs. The forebears to the modern Malamute crossed the Bering Strait with their owners over 4,000 years ago. Their size, thick coat, and work drive make them ideal dogs for pulling sleds, but they also make amicable companions.

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Changes to this dog’s profile
  • On 1/25/2023 changed name from "Corvus To Be Named" to "Corvus As the Crow Flies"
  • On 1/12/2023 changed name from "Sora" to "Corvus To Be Named"

Health Summary

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Sora has one variant that you should let your vet know about.

ALT Activity

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Sora inherited one copy of the variant we tested

Why is this important to your vet?

Sora has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Sora has this genotype, as ALT is often used as an indicator of liver health and Sora is likely to have a lower than average resting ALT activity. As such, an increase in Sora’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency (F7 Exon 5)

Identified in Alaskan Malamutes

Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant)

Identified in Alaskan Malamutes

Primary Ciliary Dyskinesia, PCD (NME5, Alaskan Malamute Variant)

Identified in Alaskan Malamutes

Alaskan Malamute Polyneuropathy, AMPN (NDRG1 SNP)

Identified in Alaskan Malamutes

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Sora’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A388

Map

A1a

Corvus As the Crow Flies’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A388

Corvus As the Crow Flies’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Staffordshire Terriers, Labrador Retrievers, and English Bulldogs.

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Sora inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Sora is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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