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Snow

Mixed Ancestry

“Snow came to Top of the Hill as a surrogate for two special orphaned boys. She came from a hoarding situation, and we don’t know much else about her. She’s nervous and flighty as to be expected from a dog raised with no socialization, but Snow is very sweet and loves cuddles if she feels safe. Her best friend is Tsar and she loves him more than anything.”

Current Location

Phelps, Wisconsin, USA

From

Blue Mounds, Wisconsin, USA

This dog has been viewed and been given 2 wags

Genetic Breed Result

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Doberman Pinscher

Doberman Pinschers are a strong and athletic breed that are built to guard and protect.

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Mastiff

Mastiffs are large but lovable dogs, known for their friendly and protective family characteristics.

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DNA Breed Origins

Breed colors:
Siberian Husky
Doberman Pinscher
Mastiff

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Here’s what Snow’s family tree may have looked like.
Snow
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Siberian Husky mix Siberian Husky / Doberman Pinscher mix Siberian Husky Mastiff / Doberman Pinscher mix Siberian Husky Doberman Pinscher Siberian Husky Siberian Husky Mastiff Doberman Pinscher mix Siberian Husky Siberian Husky Doberman Pinscher Doberman Pinscher
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Snow’s breed mix.
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Health Summary

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Snow has one variant that you should let your vet know about.

ALT Activity

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Snow inherited one copy of the variant we tested

Why is this important to your vet?

Snow has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Snow has this genotype, as ALT is often used as an indicator of liver health and Snow is likely to have a lower than average resting ALT activity. As such, an increase in Snow’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Doberman Pinschers

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Autosomal Dominant Progressive Retinal Atrophy (RHO)

Identified in Mastiffs

Canine Multifocal Retinopathy, cmr1 (BEST1 Exon 2)

Identified in Mastiffs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Mastiffs

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Deafness and Vestibular Syndrome of Dobermans, DVDob, DINGS (MYO7A)

Identified in Doberman Pinschers

Degenerative Myelopathy, DM (SOD1A)

Identified in Siberian Huskies

Dilated Cardiomyopathy, DCM1 (PDK4, Doberman Pinscher Variant 1)

Identified in Doberman Pinschers

Dilated Cardiomyopathy, DCM2 (TTN, Doberman Pinscher Variant 2)

Identified in Doberman Pinschers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Snow’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A2

Haplotype

A29a

Map

A2

Snow’s Haplogroup

A2 is a very ancient maternal line. Most likely it was one of the major female lines that contributed to the very first domesticated dogs in Central Asia about 15,000 years ago. Some of the line stayed in Central Asia to the present day, and frequently appear as Tibetan Mastiffs and Akitas. Those that escaped the mountains of Central Asia sought out other cold spots, and are now found among Alaskan Malamutes and Siberian Huskies. This lineage is also occasionally found in several common Western breeds, such as German Shepherds and Labrador Retrievers. Curiously, all New Guinea Singing Dogs descend from this line. These are an ancient and very interesting breed found in the mountains of Papua New Guinea. Unfortunately, they are now endangered. They are closely related to the Australian dingo, so you could say its cousins are dingos! This line is also common in village dogs in Southeast and East Asia. Unlike many other lineages, A2 did not spread across the whole world, probably because it did not have the opportunity to hitch its wagon to European colonialism - or because these dogs just prefer hanging out in mountains, tundras, islands, and other hard-to-reach places!

A29a

Snow’s Haplotype

Part of the A2 haplogroup, this haplotype occurs most commonly in Siberian Huskies, Alaskan Malamutes, Labrador Retrievers, and village dogs from Alaska.

Dingos commonly possess this haplogroup.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Snow inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Snow is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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