Sir Knoxville of Magic Valley Goldendoodles

“Knox”
Sir Knoxville of Magic Valley Goldendoodles

Goldendoodle

No bio has been provided yet

This dog has been viewed 551 times and been given 1 wag

Genetic Breed Result

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Goldendoodle

50.0% Golden Retriever
50.0% Poodle (Small)
Golden Retriever Golden Retriever
Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.
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Poodle (Small) Poodle (Small)
A highly intelligent and playful dog, Miniature and Toy Poodles make for great lap dogs and companions.
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Genetic Stats


Predicted Adult Weight
Genetic Age
33 human years Learn More
Based on the date of birth provided

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Knox’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Golden Retriever
Poodle (Small)

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Our algorithms predict this is the most likely family tree to explain Knox’s breed mix, but this family tree may not be the only possible one.

Health Summary

Knox is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

Knox inherited one copy of the variant we tested

How to interpret this result

Knox has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Knox inherited one copy of the variant we tested

What does this result mean?

This result should not impact Knox’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring.

What is Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2?

Golden Retriever PRA 2 is a retinal disease that causes progressive, non-painful vision loss. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.


Ichthyosis

Knox inherited one copy of the variant we tested

What does this result mean?

This result should not impact Knox’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring.

What is Ichthyosis?

This skin disorder gets its name from the thick, darkly pigmented scales of skin ("ichthys" is Greek for "fish") that affected dogs display on their noses, paw pads, and muzzles.

Breed-Relevant Genetic Conditions

Von Willebrand Disease Type I (VWF)

Identified in Small Poodles

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Golden Retrievers and Small Poodles

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1 (SLC4A3)

Identified in Golden Retrievers

Neuronal Ceroid Lipofuscinosis (CLN5 Golden Retriever Variant)

Identified in Golden Retrievers

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Small Poodles

Degenerative Myelopathy, DM (SOD1A)

Identified in Golden Retrievers

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Small Poodles

Muscular Dystrophy (DMD Golden Retriever Variant)

Identified in Golden Retrievers

Dystrophic Epidermolysis Bullosa (COL7A1)

Identified in Golden Retrievers

Osteogenesis Imperfecta (COL1A1)

Identified in Golden Retrievers

Osteochondrodysplasia (SLC13A1)

Identified in Small Poodles

Additional Genetic Conditions


Clinical Tools

Explore the genetics behind your dog’s appearance and size.
Coat Color

Coat Color

E Locus (MC1R)
No dark hairs anywhere (ee)
K Locus (CBD103)
Not expressed (KBky)
Intensity Loci LINKAGE
Any pigmented hair likely yellow or tan (Intermediate Red Pigmentation)
A Locus (ASIP)
Not expressed (ayat)
D Locus (MLPH)
Not expressed (DD)
B Locus (TYRP1)
Likely black colored nose/feet (BB)
S Locus (MITF)
Likely to have little to no white in coat (SS)
H Locus (Harlequin)
hh
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely furnished (mustache, beard, and/or eyebrows) (FI)
Coat Length (FGF5)
Likely long coat (TT)
Shedding (MC5R)
Likely light shedding (TT)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely wavy coat (CT)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Body Size

Body Size

Body Size (IGF1)
Intermediate (NI)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Intermediate (TA)
Body Size (GHR - E191K)
Larger (GG)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)

Through Knox’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A261

Map

A1a

Sir Knoxville of Magic Valley Goldendoodles’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A261

Sir Knoxville of Magic Valley Goldendoodles’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs in village dogs in Peru. Among breeds, it is most common in Golden Retrievers, Gordon Setters, and Labrador Retrievers.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

Through Knox’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.7

Map

A1b

Sir Knoxville of Magic Valley Goldendoodles’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.7

Sir Knoxville of Magic Valley Goldendoodles’s Haplotype

Part of the A1b haplogroup, this haplotype is found in village dogs from Lebanon and Indonesia. Among breeds, it is also found in Miniature Schnauzer and Toy Poodle.

Some other Embark dogs with this haplotype:

Great Danes and Pomeranians have this in common!