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Simba

Shih Tzu

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Place of Birth

Miami, Florida, USA

Current Location

Hollywood, Florida, USA

From

Miami, Florida, USA

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Genetic Breed Result

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Shih Tzu

This ancient breed is the perfect lapdog. Sweet and easygoing, they want nothing more than to be close to their humans.

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Genetic Stats

Wolfiness

0.6 % LOW

Predicted Adult Weight

12 lbs

Genetic Age
40 human years

Based on the date of birth provided

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Simba’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Simba inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Simba inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Simba is unlikely to develop this condition due to the variant. This result may be important if you decide to breed this dog - we recommend genetic testing potential mates for this condition.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Simba inherited one copy of the variant we tested

Why is this important to your vet?

Simba has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Simba has this genotype, as ALT is often used as an indicator of liver health and Simba is likely to have a lower than average resting ALT activity. As such, an increase in Simba’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Prekallikrein Deficiency

Identified in Shih Tzus

Intervertebral Disc Disease (Type I)

Identified in Shih Tzus

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Dark brown pigment
Cocoa
No impact on fur and skin color
Red Pigment Intensity LINKAGE
I (Intensity) Loci
No impact on coat pattern
Brown or Black Pigment
B (Brown) Locus
Brown fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have a mostly solid black or brown fur coat
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
Can have black masking (dark facial fur)
Saddle Tan
No impact on coat pattern
White Spotting
S (White Spotting) Locus
Likely to have some white areas in coat
Roan LINKAGE
R (Roan) Locus
Likely no impact on coat pattern
Merle
M (Merle) Locus
Unlikely to have merle pattern
Harlequin
No impact on coat pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely furnished (mustache, beard, and/or eyebrows)
Coat Length
Likely long coat
Shedding
Likely light shedding
Coat Texture
Likely wavy coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely short muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Smaller
Body Size 2
Larger
Body Size 3
Smaller
Body Size 4
Smaller
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation
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Through Simba’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A4

Haplotype

A453

Map

A4

Simba’s Haplogroup

The A4 maternal lineage is fairly rare. It is found in Cocker Spaniels, but A4 is also represented well among East Asian breeds including the Chinese Crested Dog, Shar-Pei and Shih Tzu. Moving away from Asia, it is also found among Chihuahuas (a very old breed!) and village dogs in Peru. This may be a lineage that moved into Western breeds because of their owners' tendencies to mix them up with Eastern breeds in the early modern period.

A453

Simba’s Haplotype

Part of the A4 haplogroup, the A453 haplotype occurs most commonly in Lhasa Apsos and Chihuahuas.

Some other Embark dogs with this haplotype:

The popular Chihuahua breed descends from the A4 maternal line.

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Through Simba’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B

Haplotype

H15.7

Map

B

Simba’s Haplogroup

B is a relatively rare paternal line that has only recently started to expand. The dominant lineage among the ancient Shih Tzu breed, it is also found among Tibetan Spaniels. Outside of these two breeds, B seems to be a particularly common paternal line among the village dogs of India and Southeast Asia, though it is found as far afield as Africa and down into Oceania. Considering that it is particularly diverse in northern India, it could be that this lineage hung out mostly in South Asia after the expansion of domestic dogs from Central Asia. Because it is present in Mongolia as well, it may not be surprising that ancient East Asian dog breeds are also part of this lineage. Alternatively, perhaps males representing this lineage headed north out of southern Eurasia, which eventually gave rise to the Shih Tzu and may have inspired stylistic representations of lions in ancient China!

H15.7

Simba’s Haplotype

Part of the B haplogroup, this haplotype has been found in village dogs in Qatar and India. Unlike most other haplotypes within the B haplogroup, we do see this in a select few breed dogs. Specifically, it occurs in the Shih Tzu and Tibetan Spaniel.

Some other Embark dogs with this haplotype:

The B Haplogroup is most commonly found the adorable Shih Tzu breed.

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