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Shiloh

Mixed Breed

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Genetic Breed Result

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Mixed Breed

54.9% German Shepherd Dog
30.6% Labrador Retriever
14.5% Chow Chow
German Shepherd Dog German Shepherd Dog
German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence.
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Labrador Retriever Labrador Retriever
The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.
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Chow Chow Chow Chow
This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercly loyal companion.
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Genetic Stats

Wolfiness: 1.1 % MEDIUM Learn More
Predicted Adult Weight: 81 lbs Learn More
Genetic Age: 87 human years Learn More

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Shiloh’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
German Shepherd Dog
Labrador Retriever
Chow Chow

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Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS German Shepherd Dog mix Labrador Retriever mix German Shepherd Dog Chow Chow / German Shepherd Dog mix Labrador Retriever German Shepherd Dog mix German Shepherd Dog German Shepherd Dog Chow Chow German Shepherd Dog Labrador Retriever Labrador Retriever German Shepherd Dog German Shepherd Dog mix
Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Shiloh’s breed mix, but this family tree may not be the only possible one.

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Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

1
AT RISK
2
CARRIER
162
CLEAR
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Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
This result helps your vet understand what your dog's baseline ALT activity is. The enzyme alanine aminotransferase, or ALT, is commonly used to evaluate liver health. Do…
Shiloh has two normal alleles at ALT.

At Risk for 1 genetic condition

Shiloh has tested positive for 1 of the genetic diseases that Embark tests for.
What does At Risk mean?

Testing positive is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.

Please consult with your veterinarian to determine the best course of action.

Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Carrier for 2 genetic conditions

Shiloh is a carrier for 2 of the genetic diseases that Embark tests for.
What does Carrier mean?

Shiloh has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Shiloh ever has children.

Condition List

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Common Conditions

Good news! Shiloh tested clear for 23 genetic conditions that are common in his breed mix.
Condition List

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Shiloh.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Shiloh.

Canine Leukocyte Adhesion Deficiency Type III (LAD3)
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Shiloh.

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Labrador Retrievers, but not Shiloh.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A benign disease that affects red blood cell shape, elliptocytosis rarely causes symptoms. Upon examination of a blood smear, however, affected dogs have elongated, oval …

Seen in Labrador Retrievers, Chow Chows, but not Shiloh.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Labrador Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Labrador Retrievers, but not Shiloh.

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, but not Shiloh.

Golden Retriever Progressive Retinal Atrophy 2
(TTC8)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, but not Shiloh.

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, but not Shiloh.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Shiloh.

Achromatopsia
(CNGA3 Exon 7 Labrador Retriever Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in Labrador Retrievers, but not Shiloh.

Macular Corneal Dystrophy (MCD)
(CHST6)
Eyes

A disease of middle-aged dogs, MCD was first characterized in the Labrador Retriever. Affected dogs begin to show clouding of the eyes and visual impairment due to abnorm…

Seen in Labrador Retrievers, but not Shiloh.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Shiloh.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Shiloh.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Shiloh.

Narcolepsy
(HCRTR2 Intron 6)
Brain and Spinal Cord

A neurologic condition characterized by daytime sleepiness and fragmented sleep cycles, affected dogs also exhibit episodes of cataplexy, a sudden complete loss of muscle…

Seen in Labrador Retrievers, but not Shiloh.

Centronuclear Myopathy
(PTPLA)
Muscular

This muscle disorder is characterized by exercise intolerance, weight loss, and muscle wasting. While abnormal tendon reflexes can be observed as early as 1 month, the sy…

Seen in Labrador Retrievers, but not Shiloh.

Myotubular Myopathy 1, X-linked Myotubular Myopathy
(MTM1)
Muscular

This is a degenerative muscle disease first characterized in the Labrador Retriever. Affected dogs present as puppies with failure to thrive and weakness; this rapidly pr…

Seen in Labrador Retrievers, but not Shiloh.

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Seen in German Shepherd Dogs, Labrador Retrievers, Chow Chows, but not Shiloh.

Congenital Myasthenic Syndrome
(COLQ)
Neuro-muscular

This is a non-progressive disease characterized by episodes of exercise intolerance and weakness; some forms have been shown to respond to medical treatment. Though it ha…

Seen in Labrador Retrievers, but not Shiloh.

Hereditary Nasal Parakeratosis
(SUV39H2)
Skin & Connective Tissues

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog. HNPK isn't usually as upsetting to the dog as it …

Seen in Labrador Retrievers, but not Shiloh.

Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia
(COL9A3, Labrador Retriever)
Skeletal

A developmental disease described in the Labrador Retriever and the Samoyed, affected dogs can show signs very early in life and can include dramatic short-limbed dwarfis…

Seen in Labrador Retrievers, but not Shiloh.

Skeletal Dysplasia 2
(COL11A2)
Skeletal

A disease of skeletal development, this causes dogs to have abnormally short legs but similar body lengths compared to unaffected dogs, and can be observed by the time do…

Seen in Labrador Retrievers, but not Shiloh.

Other Conditions: Clear of 139

Shiloh is clear of 139 other genetic diseases that Embark tests for.

Explore:

Family tree

Traits

Maternal Haplotype

Paternal Haplotype

Jump to:

Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
ee
K Locus (Dominant Black)
KBky
A Locus (Agouti, Sable)
ata
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red)
Bb

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
GT
Shedding (MC5R)
CT
Curly Coat (KRT71)
CC
Hairlessness (FOXI3)
LINKAGE
N/N

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NN
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GG
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Shiloh’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A225

Map

A1e

Shiloh’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A225

Shiloh’s Haplotype

Part of the large A1e haplogroup, we have spotted this haplotype in village dogs in South America and Papua New Guinea. Among breeds, we see this haplotype most frequently in Border Collies, Australian Cattle Dogs, and Australian Shepherd Dogs.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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Family tree

Health

Traits

Paternal Haplotype

Through Shiloh’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.15

Map

A1a

Shiloh’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.15

Shiloh’s Haplotype

Part of the large A1a haplogroup, this haplotype is found in village dogs from across the globe (outside of Asia). As for breeds, it is primarily seen in German Shepherds, Labrador Retrievers, Nova Scotia Duck Tolling Retriever. It is by far the most common haplotype in German Shepherds.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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Family tree

Health

Traits

Maternal Haplotype