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Sherlock

Mixed Ancestry

“He has a peculiar ritual at bedtime of fluffing, tugging at, nudging, & rearranging his blanket. He communicates hunger or desire to go outside by huffing & puffing, yodeling, and finally - if I tease him a little bit by pretending not to notice - a distinctive shout that I describe as a cross between a bark and a yelp. He also absolutely loves people and other dogs. Whenever he sees one of either, even at long distances, he whines lightly until he gets to greet them and/or play with them.”

Place of Birth

USA

Current Location

Phoenix, Arizona, USA

This dog has been viewed and been given 6 wags

Genetic Breed Result

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Anatolian Shepherd Dog

The Anatolian Shepherd Dog is a native of Turkey, where he was developed as a shepherd’s companion and livestock guardian. He was bred to resemble the size and color of the livestock he defended so predators would not detect him among the flock. Sometimes called the Anatolian Karabash Dog, he’s a fiercely loyal guard dog and a large, impressive dog breed, weighing 120 to 150 pounds at maturity.

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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Rottweiler

Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.

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Dogs Like Sherlock

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Discover dogs who share a similar breed mix to Sherlock. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Anatolian Shepherd Dog
American Pit Bull Terrier
Boxer
Rottweiler

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Here’s what Sherlock’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Sherlock’s breed mix.

Breed Reveal Video

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Health Summary

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Sherlock has one variant that you should let your vet know about.

ALT Activity

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Sherlock inherited one copy of the variant we tested

Why is this important to your vet?

Sherlock has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Sherlock has this genotype, as ALT is often used as an indicator of liver health and Sherlock is likely to have a lower than average resting ALT activity. As such, an increase in Sherlock’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Hemophilia A

Identified in Boxers

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Urate Kidney & Bladder Stones

Identified in American Pit Bull Terriers

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

Degenerative Myelopathy, DM

Identified in Boxers

Neuroaxonal Dystrophy, NAD

Identified in Rottweilers

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Juvenile Laryngeal Paralysis and Polyneuropathy

Identified in Rottweilers

Hereditary Footpad Hyperkeratosis

Identified in Rottweilers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Sherlock’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A11a/419

Map

A1d

Sherlock’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A11a/419

Sherlock’s Haplotype

Part of the A1d haplogroup, this haplotype occurs most frequently in Yorkshire Terriers, Old English Sheepdogs, and Miniature Schnauzers.

The vast majority of Rottweilers have the A1d haplogroup.

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Through Sherlock’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H7.3

Map

D

Sherlock’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H7.3

Sherlock’s Haplotype

Part of the D haplogroup, the H7.3 haplotype occurs most commonly in Salukis and Tibetan Mastiffs. We've also spotted it in Middle Eastern Village Dogs and European Village Dogs.

The D paternal lineage is common in Boxers.

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