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Shadow

Yorkshire Terrier

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“Shadow was born 12/10/2008 and we adopted him on 02/25/2009 from a breeder in Los Angeles, at 8-9 weeks old. He was part of a larger litter but most of his siblings were adopted before him, except for a sister that accompanied him the day we got him. Anyone who met Shadow always remarked on his unusually large size for a Yorkie (15 lbs). There were doubts about his purebred background, and we thought he was likely mixed. Turns out the breeder was right. Shadow passed away on May 19, 2022”

Current Location

Los Angeles, California, USA

From

Los Angeles, California, USA

This dog has been viewed and been given 3 wags

Genetic Breed Result

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Yorkshire Terrier

Petite but proud, the Yorkshire terrier is a popular toy breed with a silky, low-shedding coat.

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Shadow’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Shadow inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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Shadow inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Shadow is unlikely to develop this condition due to the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Dilated Cardiomyopathy, DCM1

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Shadow inherited one copy of the variant we tested

What does this result mean?

Our research indicates that this genetic variant is not likely to increase the risk that Shadow will develop this disease.

Scientific Basis

Dogs with similar breeds to Shadow are not likely to have increased risk of developing the disease. Research has indicated increased risk in other breeds that are not found in Shadow.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Shadow inherited both copies of the variant we tested

Why is this important to your vet?

Shadow has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Shadow's ALT activity above their current, healthy, ALT activity. As an increase above Shadow’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd

Identified in Yorkshire Terriers

Primary Lens Luxation

Identified in Yorkshire Terriers

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Shadow’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A271

Map

A1d

Shadow’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A271

Shadow’s Haplotype

Part of the large A1d haplogroup, this haplotype occurs most commonly in Yorkshire Terriers, English Springer Spaniels, and village dogs in Colombia.

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

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Through Shadow’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.26

Map

A1a

Shadow’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.26

Shadow’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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