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Rusty

Mixed Ancestry

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Genetic Breed Result

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Great Pyrenees

The Great Pyrenees is an exceptionally loving dog whose primary function is to protect sheep, goats, livestock, people, children, grass, flowers, the moon, lawn furniture, etc., from any real or imaginary predators that may intrude on your personal space. They have a strong build and an amazing thick white coat that exudes elegance and majesty. They make a great family dog because of their intelligence and steady temperament.

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Australian Cattle Dog

A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.

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Miniature/MAS-type Australian Shepherd

Miniature American Shepherds (also known as Miniature Australian Shepherds, or Mini Aussies) have the trainability, intelligence and energy of the larger Aussie cousins, and excel at outdoors activities and agility competitions.

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Border Collie

Border Collies are highly energetic and work-oriented herding dogs, whose stamina is matched by their intelligence and alertness. While they excel at the herding they were bred for, many Border Collies also enjoy flyball, obedience, and other canine sports. As long as they have a job to do and are physically and mentally stimulated, Border Collies can make excellent companions for the right owners.

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Dogs Like Rusty

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Discover dogs who share a similar breed mix to Rusty. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Great Pyrenees
Australian Cattle Dog
Miniature/MAS-type Australian Shepherd
Border Collie

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Here’s what Rusty’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Rusty’s breed mix.
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Health Summary

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Rusty has one variant that you should let your vet know about.

ALT Activity

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Rusty inherited one copy of the variant we tested

Why is this important to your vet?

Rusty has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Rusty has this genotype, as ALT is often used as an indicator of liver health and Rusty is likely to have a lower than average resting ALT activity. As such, an increase in Rusty’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Cattle Dogs, Border Collies, and more

Trapped Neutrophil Syndrome, TNS

Identified in Border Collies

Progressive Retinal Atrophy, prcd

Identified in Australian Cattle Dogs and Miniature/MAS-type Australian Shepherds

Collie Eye Anomaly

Identified in Australian Cattle Dogs, Border Collies, and more

Canine Multifocal Retinopathy, cmr1

Identified in Great Pyrenees and Miniature/MAS-type Australian Shepherds

Hereditary Cataracts

Identified in Miniature/MAS-type Australian Shepherds

Primary Lens Luxation

Identified in Australian Cattle Dogs and Border Collies

Cystinuria Type II-A

Identified in Australian Cattle Dogs

Urate Kidney & Bladder Stones

Identified in Miniature/MAS-type Australian Shepherds

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Australian Cattle Dogs and Border Collies

Neuronal Ceroid Lipofuscinosis 6, NCL 6

Identified in Miniature/MAS-type Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Cattle Dogs and Miniature/MAS-type Australian Shepherds

Degenerative Myelopathy, DM

Identified in Great Pyrenees

Myotonia Congenita

Identified in Australian Cattle Dogs and Border Collies

Cobalamin Malabsorption

Identified in Border Collies

Craniomandibular Osteopathy, CMO

Identified in Miniature/MAS-type Australian Shepherds

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Rusty’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B47

Map

B1

Rusty’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B47

Rusty’s Haplotype

Part of the large B1 haplogroup, we have spotted this haplotype in village dogs in South America, Africa, the Middle East, and South Asia. Among the 8 breeds we have sampled it in, this haplotype occurs most frequently in Newfoundlands, Australian Cattle Dogs, and Pembroke Welsh Corgis.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Rusty’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H10.2

Map

D

Rusty’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H10.2

Rusty’s Haplotype

Part of the D haplogroup, we have detected this rare haplotype in village dogs in Qatar.

The D paternal lineage is common in Boxers.

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