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Ruby Rose Esler

Mixed Breed

“Very sweet and Sensitive little girl. Love sticks and kissing People and other dogs.”

Place of Birth
Alabama, USA
Current Location
Minnesota, USA
From
Alabama, USA

This dog has been viewed 100 times and been given 11 wags

Genetic Breed Result

Learn how it’s done

Mixed Breed

34.0% American Bulldog
24.2% American Bully
16.1% Border Collie
16.0% Labrador Retriever
9.7% Australian Shepherd
American Bulldog American Bulldog
American bulldogs are enjoying a healthy increase in popularity, either as a working/protector dog or as a family pet. All over the world, they are used variously as "hog dogs" (catching escaped pigs or hunting razorbacks), as cattle drovers and as working or sport K-9s. American Bulldogs also successfully compete in several dog sports such as dog obedience, Iron Dog competition and weight pulling.
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American Bully American Bully
The American Bully may look intimidating with its muscular build, but these dogs are bred to be the ideal family or companion dog. This breed is notable for coming in several different size and type varieties, so there's a lot of diversity in their appearance. They're a newer breed, originating in the 80s and 90s in the United States.
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Border Collie Border Collie
Border Collies are highly energetic and work oriented herding dogs, whose stamina is matched by their intelligence and alertness. If you want the smartest dog out there, then you have come to the right place!
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Labrador Retriever Labrador Retriever
The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.
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Australian Shepherd Australian Shepherd
Australian Shepherds are an energetic mid-sized breed that make the perfect companion.
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Genetic Stats


Wolfiness

0.0 % LOW Learn More

Predicted Adult Weight
Genetic Age
22 human years Learn More
Based on the date of birth provided

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Ruby Rose Esler’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
American Bulldog
American Bully
Border Collie
Labrador Retriever
Australian Shepherd

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS American Bully mix American Bulldog mix American Bully Border Collie / Australian Shepherd mix American Bulldog Labrador Retriever / American Bulldog mix American Bully American Bully Border Collie Australian Shepherd mix American Bulldog American Bulldog Labrador Retriever American Bulldog mix

Breed Reveal Video

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Our algorithms predict this is the most likely family tree to explain Ruby Rose Esler’s breed mix, but this family tree may not be the only possible one.

Summary

0
AT RISK
1
CARRIER
174
CLEAR
Tap above or scroll down to see more

Clinical Tools

These clinical tools are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal

Ruby Rose Esler has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Ruby Rose Esler has this genotype, as ALT is often used as an indicator of liver health and Ruby Rose Esler is likely to have a lower than average resting ALT activity. As such, an increase in Ruby Rose Esler’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

Genetic Health Conditions

A genetic health condition indicates a genetic mutation that increases the risk that an animal develops a specific disease.

Not At Risk

Good news! Ruby Rose Esler did not test positive for any of the genetic conditions that Embark screens for.

It is still important to let your veterinarian know these results because they could help guide Ruby Rose Esler’s diagnosis and treatment if she gets sick in the future.

Carrier for
1 genetic condition

Ruby Rose Esler is a carrier for 1 of the genetic diseases that Embark tests for.
What does Carrier mean?

Ruby Rose Esler has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Ruby Rose Esler ever has children.

Condition List

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Common Conditions

Good news! Ruby Rose Esler tested clear for 33 genetic conditions that are common in her breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Border Collies, Australian Shepherds, but not Ruby Rose Esler.

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A benign disease that affects red blood cell shape, elliptocytosis rarely causes symptoms. Upon examination of a blood smear, however, affected dogs have elongated, oval …

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Labrador Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Trapped Neutrophil Syndrome
(VPS13B)
Blood

Dogs with TNS are prone to recurrent bacterial infections that must be recognized and treated early. Neutrophils, a type of white blood cells, are generated in the bone m…

Seen in Border Collies, but not Ruby Rose Esler.

Progressive Retinal Atrophy, prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Labrador Retrievers, Australian Shepherds, but not Ruby Rose Esler.

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2
(TTC8)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Progressive Retinal Atrophy, crd1
(PDE6B)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in American Bullys, but not Ruby Rose Esler.

Progressive Retinal Atrophy, crd2
(IQCB1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in American Bullys, but not Ruby Rose Esler.

Collie Eye Anomaly, Choroidal Hypoplasia, CEA
(NHEJ1)
Eyes

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia and is a developmental disease of the choroid. The ch…

Seen in Border Collies, Australian Shepherds, but not Ruby Rose Esler.

Achromatopsia
(CNGA3 Exon 7 Labrador Retriever Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Canine Multifocal Retinopathy
cmr1 (BEST1 Exon 2)
Eyes

This is a non-progressive retinal disease that, in rare cases, can lead to vision loss. CMR is typically only identified when a vet examines the eye which, in dogs with C…

Seen in American Bulldogs, American Bullys, Australian Shepherds, but not Ruby Rose Esler.

Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts
(HSF4 Exon 9 Shepherd Variant)
Eyes

One of the leading causes of blindness in dogs (and humans!), cataracts are a progressive disease of the lens that causes functional blindness, but can be surgically corr…

Seen in Australian Shepherds, but not Ruby Rose Esler.

Macular Corneal Dystrophy, MCD
(CHST6)
Eyes

A disease of middle-aged dogs, MCD was first characterized in the Labrador Retriever. Affected dogs begin to show clouding of the eyes and visual impairment due to abnorm…

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Hyperuricosuria and Hyperuricemia or Urolithiasis, HUU
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in American Bulldogs, American Bullys, Australian Shepherds, but not Ruby Rose Esler.

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia, NCL-A
(ARSG Exon 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in American Bullys, but not Ruby Rose Esler.

Neuronal Ceroid Lipofuscinosis 1, NCL 1
(CLN5 Border Collie Variant)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Border Collies, but not Ruby Rose Esler.

Neuronal Ceroid Lipofuscinosis 6, NCL 6
(CLN6 Exon 7)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Shepherds, but not Ruby Rose Esler.

Neuronal Ceroid Lipofuscinosis
(CLN8 Australian Shepherd Variant)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Shepherds, but not Ruby Rose Esler.

Neuronal Ceroid Lipofuscinosis 10, NCL 10
(CTSD Exon 5)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in American Bulldogs, American Bullys, but not Ruby Rose Esler.

L-2-Hydroxyglutaricaciduria, L2HGA
(L2HGDH)
Brain and Spinal Cord

Currently there is no definitive treatment for L2HGA; rather, the condition is managed with anti-seizure and anti-anxiety medications. A rare metabolic disorder, this can…

Seen in American Bullys, but not Ruby Rose Esler.

Narcolepsy
(HCRTR2 Intron 6)
Brain and Spinal Cord

A neurologic condition characterized by daytime sleepiness and fragmented sleep cycles, affected dogs also exhibit episodes of cataplexy, a sudden complete loss of muscle…

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Centronuclear Myopathy
(PTPLA)
Muscular

This muscle disorder is characterized by exercise intolerance, weight loss, and muscle wasting. While abnormal tendon reflexes can be observed as early as 1 month, the sy…

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Myotonia Congenita
(CLCN1 Exon 23)
Muscular

This condition is characterized by prolonged muscle contraction and stiffness that usually resolves with normal exercise, though physical therapy can be beneficial. The g…

Seen in Border Collies, but not Ruby Rose Esler.

Myotubular Myopathy 1, X-linked Myotubular Myopathy, XL-MTM
(MTM1, Labrador Variant)
Muscular

This is a degenerative muscle disease first characterized in the Labrador Retriever. Affected dogs present as puppies with failure to thrive and weakness; this rapidly pr…

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption
(CUBN Exon 53)
Gastrointestinal

This is a treatable gastrointestinal disease where dogs cannot absorb cobalamin, often causing them to be runty with poor energy levels. Cobalamin is required for synthes…

Seen in Border Collies, but not Ruby Rose Esler.

Congenital Myasthenic Syndrome
(COLQ)
Neuromuscular

This is a non-progressive disease characterized by episodes of exercise intolerance and weakness; some forms have been shown to respond to medical treatment. Though it ha…

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Ichthyosis
(NIPAL4)
Skin & Connective Tissues

This skin disorder gets its name from the thick, darkly pigmented scales of skin ("ichthys" is Greek for "fish") that affected dogs display on their noses, paw pads, and …

Seen in American Bulldogs, American Bullys, but not Ruby Rose Esler.

Hereditary Nasal Parakeratosis
(SUV39H2)
Skin & Connective Tissues

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog. HNPK isn't usually as upsetting to the dog as it …

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia, OSD1
(COL9A3, Labrador Retriever)
Skeletal

A developmental disease described in the Labrador Retriever and the Samoyed, affected dogs can show signs very early in life and can include dramatic short-limbed dwarfis…

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Skeletal Dysplasia 2, SD2
(COL11A2)
Skeletal

A disease of skeletal development, this causes dogs to have abnormally short legs but similar body lengths compared to unaffected dogs, and can be observed by the time do…

Seen in Labrador Retrievers, but not Ruby Rose Esler.

Craniomandibular Osteopathy, CMO
(SLC37A2)
Skeletal

A noncancerous, proliferative bone disease that commonly affects the lower jaw and tympanic bullae, CMO is best known in the West Highland White Terrier, Scottish Terrier…

Seen in Australian Shepherds, but not Ruby Rose Esler.

Other Conditions:
Clear of 141

Ruby Rose Esler is clear of 141 other genetic conditions that Embark tests for.
Explore the genetics behind your dog’s appearance, size, and genetic diversity.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
No Call
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have patterned fur
Body Pattern
A (Agouti) Locus
Agouti (Wolf Sable) coat color pattern
Facial Fur Pattern
E (Extension) Locus
No dark mask or grizzle facial fur patterns
Saddle Tan
No impact on coat pattern
Merle
M (Merle) Locus
Unlikely to have merle pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Intermediate
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation

Through Ruby Rose Esler’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A427

Map

A1e

Ruby Rose Esler’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A427

Ruby Rose Esler’s Haplotype

Part of the A1e haplogroup, this haplotype occurs most frequently in Australian Cattle Dogs.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Ruby Rose Esler inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Ruby Rose Esler is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.