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Ruby

Mixed Breed

“Rescue pup found in a Louisiana parking lot. Brought to San Diego by Thrive Rescue.”

Place of Birth
Louisiana, USA
Current Location
San Diego, California, USA
From
Thrive Animal Rescue, Old El Camino Real, San Diego, CA, USA

This dog has been viewed 489 times and been given 1 wag

Genetic Breed Result

Learn how it’s done

Mixed Breed

24.5% Bloodhound
19.4% Great Dane
10.4% American Pit Bull Terrier
10.2% Labrador Retriever
8.6% German Shepherd Dog
6.1% Rottweiler
6.0% Weimaraner
14.8% Supermutt

Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Bloodhound Bloodhound
Bloodhounds are large, substantial dogs standing 23 to 27 inches at the shoulder and weighing up to 110 pounds. Their most famous features are a long, wrinkled face with loose-hanging skin; huge drooping ears; and warm, deep-set eyes that complete an expression of solemn dignity. The coat color can be black and tan, liver (reddish brown) and tan, or red. A thick, powerful body and legs allow Bloodhounds to follow a trail over miles of tough, punishing terrain.
Learn More
Great Dane Great Dane
Great Danes are large lovable dogs that need exercise and space. Many Great Danes are "leaners"-- they lean against their people to be closer to them, seemingly oblivious to their size!
Learn More
American Pit Bull Terrier American Pit Bull Terrier
The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.
Learn More
Labrador Retriever Labrador Retriever
The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.
Learn More
German Shepherd Dog German Shepherd Dog
German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.
Learn More
Rottweiler Rottweiler
Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.
Learn More
Weimaraner Weimaraner
The Weimaraner is an all-purpose gun dog. The name comes from the Grand Duke of Saxe-Weimar-Eisenach, Karl August, whose court, based in the city of Weimar (now in the state of Thuringia in modern-day Germany), enjoyed hunting.
Learn More
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Genetic Stats


Wolfiness

0.8 % MEDIUM Learn More

Predicted Adult Weight
Genetic Age
25 human years Learn More
Based on the date of birth provided

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Ruby’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Bloodhound
Great Dane
American Pit Bull Terrier
Labrador Retriever
German Shepherd Dog
Rottweiler
Weimaraner
Supermutt

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Bloodhound mix American Pit Bull Terrier / Weimaraner mix Labrador Retriever / German Shepherd Dog mix Bloodhound Great Dane / Rottweiler mix American Pit Bull Terrier Weimaraner mix Labrador Retriever German Shepherd Dog mix Bloodhound Bloodhound Great Dane Rottweiler mix

Our algorithms predict this is the most likely family tree to explain Ruby’s breed mix, but this family tree may not be the only possible one.

Summary

0
AT RISK
0
CARRIER
167
CLEAR
Tap above or scroll down to see more

Clinical Traits

These clinical traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal

Ruby has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Ruby has this genotype, as ALT is often used as an indicator of liver health and Ruby is likely to have a lower than average resting ALT activity. As such, an increase in Ruby’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

Genetic Health Conditions

A genetic health condition indicates a genetic mutation that increases the risk that an animal develops a specific disease.

Not At Risk

Good news! Ruby did not test positive for any of the genetic conditions that Embark screens for.

It is still important to let your veterinarian know these results because they could help guide Ruby’s diagnosis and treatment if she gets sick in the future.

Not A Carrier

Good news! Ruby is not a carrier for any of the genetic conditions that Embark tests for.

Common Conditions

Good news! Ruby tested clear for 33 genetic conditions that are common in her breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, but not Ruby.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Ruby.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Ruby.

Canine Leukocyte Adhesion Deficiency Type III, LAD3
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Ruby.

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Labrador Retrievers, but not Ruby.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A benign disease that affects red blood cell shape, elliptocytosis rarely causes symptoms. Upon examination of a blood smear, however, affected dogs have elongated, oval …

Seen in Labrador Retrievers, but not Ruby.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Labrador Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Labrador Retrievers, but not Ruby.

Progressive Retinal Atrophy, prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Labrador Retrievers, but not Ruby.

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2
(TTC8)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Labrador Retrievers, but not Ruby.

Progressive Retinal Atrophy, crd1
(PDE6B)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in American Pit Bull Terriers, but not Ruby.

Progressive Retinal Atrophy, crd2
(IQCB1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in American Pit Bull Terriers, but not Ruby.

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Labrador Retrievers, but not Ruby.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Ruby.

Achromatopsia
(CNGA3 Exon 7 Labrador Retriever Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in Labrador Retrievers, but not Ruby.

Macular Corneal Dystrophy, MCD
(CHST6)
Eyes

A disease of middle-aged dogs, MCD was first characterized in the Labrador Retriever. Affected dogs begin to show clouding of the eyes and visual impairment due to abnorm…

Seen in Labrador Retrievers, but not Ruby.

Hyperuricosuria and Hyperuricemia or Urolithiasis, HUU
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in American Pit Bull Terriers, German Shepherd Dogs, Weimaraners, but not Ruby.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Ruby.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis, RCND
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Ruby.

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Ruby.

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia, NCL-A
(ARSG Exon 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in American Pit Bull Terriers, but not Ruby.

Degenerative Myelopathy, DM
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Bloodhounds, German Shepherd Dogs, but not Ruby.

Hypomyelination and Tremors
(FNIP2)
Brain and Spinal Cord

This group of diseases center around the neuronal axon, a specialized cellular structure that helps our nervous systems relay information across great distances. Remember…

Seen in Weimaraners, but not Ruby.

Narcolepsy
(HCRTR2 Intron 6)
Brain and Spinal Cord

A neurologic condition characterized by daytime sleepiness and fragmented sleep cycles, affected dogs also exhibit episodes of cataplexy, a sudden complete loss of muscle…

Seen in Labrador Retrievers, but not Ruby.

Juvenile Laryngeal Paralysis and Polyneuropathy, Polyneuropathy with Ocular Abnormalities and Neuronal Vacuolation, POANV
(RAB3GAP1, Rottweiler Variant)
Brain and Spinal Cord

First characterized in Rottweilers and Black Russian Terriers, puppies affected with JLPP tend to show signs as early as 3 months of age. Due to weakening or paralysis of…

Seen in Rottweilers, but not Ruby.

Centronuclear Myopathy
(PTPLA)
Muscular

This muscle disorder is characterized by exercise intolerance, weight loss, and muscle wasting. While abnormal tendon reflexes can be observed as early as 1 month, the sy…

Seen in Labrador Retrievers, but not Ruby.

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Seen in Labrador Retrievers, but not Ruby.

Inherited Myopathy of Great Danes
(BIN1)
Muscular

This muscle wasting disease causes young dogs to present with weakness, unsteady gait, generalized muscle wasting, and exercise intolerance. The severity of the disease c…

Seen in Great Danes, but not Ruby.

Myotubular Myopathy 1, X-linked Myotubular Myopathy, XL-MTM
(MTM1, Labrador Variant)
Muscular

This is a degenerative muscle disease first characterized in the Labrador Retriever. Affected dogs present as puppies with failure to thrive and weakness; this rapidly pr…

Seen in Labrador Retrievers, but not Ruby.

Congenital Myasthenic Syndrome
(COLQ)
Neuromuscular

This is a non-progressive disease characterized by episodes of exercise intolerance and weakness; some forms have been shown to respond to medical treatment. Though it ha…

Seen in Labrador Retrievers, but not Ruby.

Ichthyosis
(SLC27A4)
Skin & Connective Tissues

This skin disorder gets its name from the thick, darkly pigmented scales of skin (“ichthys” is Greek for “fish”) that affected dogs display on their noses, paw pads, and …

Seen in Great Danes, but not Ruby.

Hereditary Nasal Parakeratosis
(SUV39H2)
Skin & Connective Tissues

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog. HNPK isn't usually as upsetting to the dog as it …

Seen in Labrador Retrievers, but not Ruby.

Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia, OSD1
(COL9A3, Labrador Retriever)
Skeletal

A developmental disease described in the Labrador Retriever and the Samoyed, affected dogs can show signs very early in life and can include dramatic short-limbed dwarfis…

Seen in Labrador Retrievers, but not Ruby.

Skeletal Dysplasia 2, SD2
(COL11A2)
Skeletal

A disease of skeletal development, this causes dogs to have abnormally short legs but similar body lengths compared to unaffected dogs, and can be observed by the time do…

Seen in Labrador Retrievers, but not Ruby.

Other Conditions:
Clear of 134

Ruby is clear of 134 other genetic conditions that Embark tests for.
Explore the genetics behind your dog’s appearance, size, and genetic diversity.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have a mostly solid black or brown fur coat
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
Can have black masking (dark facial fur)
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely light to moderate shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Short/natural bobtail
Hind Dew Claws
Unlikely to have hind dew claws
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Larger
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance

Through Ruby’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A234

Map

A1e

Ruby’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A234

Ruby’s Haplotype

Part of the large A1e haplogroup, this haplotype occurs in village dogs in South America, South Asia, and into the South Pacific. Among breeds, we see it in highest frequency among Vizslas, Boxers, and Yorkshire Terriers.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

This 'Paternal Haplotype' tab is for deep ancestral lineage going back thousands of years.

For recent ancestry—"What breeds did my dog inherit from her mom and dad?"—please refer to the Breed, Family Tree, or Summary tab.

The Paternal Haplotype refers to a dog’s deep ancestral lineage stretching back thousands of years, before there were any distinct breeds of dog. We determine the Paternal Haplotype by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Ruby is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.