Venn diagram

Compare your dogs to Roxy Select one to begin:

“Roxy”
Roxy of Petite Posh

No bio has been provided yet

This dog has been viewed and been given 0 wags

Registration

American Kennel Club (AKC):

Loading...

Start a conversation! Message this dog’s owner.

Loading...

Explore

Health Summary

warn icon

Roxy inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, rcd3

warn icon

Roxy inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Roxy’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Roxy is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Progressive Retinal Atrophy, rcd3?

PRA-rcd3 is a retinal disease that causes progressive, non-painful vision loss. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.

ALT Activity

warn icon

Roxy inherited one copy of the variant we tested

Why is this important to your vet?

Roxy has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Roxy has this genotype, as ALT is often used as an indicator of liver health and Roxy is likely to have a lower than average resting ALT activity. As such, an increase in Roxy’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

good icon

Thrombopathia (RASGRP1 Exon 5, American Eskimo Dog Variant)

Identified in American Eskimo Dogs

Methemoglobinemia (CYB5R3)

Identified in Pomeranians

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in American Eskimo Dogs

Primary Lens Luxation (ADAMTS17)

Identified in American Eskimo Dogs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Pomeranians

Degenerative Myelopathy, DM (SOD1A)

Identified in American Eskimo Dogs

Oculocutaneous Albinism, OCA (SLC45A2, Small Breed Variant)

Identified in Pekingese and Pomeranians

Hereditary Vitamin D-Resistant Rickets (VDR)

Identified in Pomeranians

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Pekingese

Additional Genetic Conditions

good icon

Explore

Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

Loading...

Explore