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Roxanne

Beagle

“Roxanne was purchased from a back yard breeder in a small town in Western Washington in 2006 before I knew much at all about dogs. Roxy is a confident hound girl who whelped 2 litters of puppies with our neighbor's Beagle, Doogie. One litter of 6 (2 females, 4 males) in ~2008 and one litter of 10 (all males) in ~2010. She has a calm demeanor with some resource guarding and is starting to slow down, but is our favorite old girl.”

Place of Birth
Dryad, WA, USA
Current Location
Seattle, Washington, USA
From
Dryad, WA, USA

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Genetic Breed Result

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Beagle

100.0% Beagle
Beagle Beagle
The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.
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Genetic Stats


Wolfiness

0.9 % MEDIUM Learn More

Predicted Adult Weight
Genetic Age
90 human years Learn More
Based on the date of birth provided

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Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Roxanne’s breed mix, but this family tree may not be the only possible one.

Summary

1
AT RISK
1
CARRIER
171
CLEAR
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Clinical Traits

These clinical traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal

Roxanne has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Roxanne's ALT activity above their current, healthy, ALT activity. As an increase above Roxanne’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

Genetic Health Conditions

A genetic health condition indicates a genetic mutation that increases the risk that an animal develops a specific disease.

At Risk for 1 genetic condition

Roxanne has tested positive for 1 of the genetic conditions that Embark tests for.
What does At Risk mean?

Testing positive is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.

Please consult with your veterinarian to determine the best course of action.

Condition List

Chondrodystrophy and Intervertebral Disc Disease, CDDY/IVDD, Type I IVDD
(FGF4 retrogene - CFA12)
Skeletal

Chondrodystrophy (CDDY) refers to the "long and low" body shape characteristic of many dog breeds including Dachshunds and Corgis. Recently, a mutation was discovered tha…

Carrier for
1 genetic condition

Roxanne is a carrier for 1 of the genetic diseases that Embark tests for.
What does Carrier mean?

Roxanne has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Roxanne ever has children.

Condition List

Hypocatalasia, Acatalasemia
(CAT)
Metabolic

This condition causes no ill effects in the majority of dogs; however, some dogs can suffer from mouth ulcers leading to difficulty eating and increased susceptibility to…

Common Conditions

Good news! Roxanne tested clear for 9 genetic conditions that are common in her breed.
Condition List

Factor VII Deficiency
(F7 Exon 5)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Pyruvate Kinase Deficiency
(PKLR Exon 7 Beagle Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Glaucoma
Primary Open Angle Glaucoma (ADAMTS10 Exon 17)
Eyes

A disease that affects humans and dogs alike; this is an adult-onset, medically manageable condition that causes high intraocular pressure (IOP). If left untreated, it ca…

Cerebellar Abiotrophy, Neonatal Cerebellar Cortical Degeneration, NCCD
(SPTBN2)
Brain and Spinal Cord

Known as the “oldest” (even reptiles and more ancient species have them!) part of the brain, the cerebellum fine-tunes motor signals from the brain to the muscles, allowi…

Fetal-Onset Neonatal Neuroaxonal Dystrophy
(MFN2)
Brain and Spinal Cord

This group of diseases center around the neuronal axon, a specialized cellular structure that helps our nervous systems relay information across great distances. Remember…

Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption
(CUBN Exon 8)
Gastrointestinal

This is a treatable gastrointestinal disease where dogs cannot absorb cobalamin, often causing them to be runty with poor energy levels. Cobalamin is required for synthes…

Musladin-Lueke Syndrome
(ADAMTSL2)
Skin & Connective Tissues

First characterized in the Beagle, this condition causes abnormally strong connections between the structural proteins that provide strength and integrity to tissues like…

Osteogenesis Imperfecta, Brittle Bone Disease
(COL1A2)
Skeletal

A disease of bone strength and flexibilty, affected dogs often present to the vet for spontaneous bone fractures, tooth fractures and loss, and joint pain; these symptoms…

Other Conditions:
Clear of 162

Roxanne is clear of 162 other genetic conditions that Embark tests for.
Explore the genetics behind your dog’s appearance, size, and genetic diversity.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have patterned fur
Body Pattern
A (Agouti) Locus
Black/Brown and tan coat color pattern
Facial Fur Pattern
E (Extension) Locus
No dark mask or grizzle facial fur patterns
Saddle Tan
Likely saddle tan patterned
Merle
M (Merle) Locus
Unlikely to have merle pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Smaller
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Smaller
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation

Through Roxanne’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1b

Map

B1

Roxanne’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1b

Roxanne’s Haplotype

Part of the large B1 haplogroup, we see this haplotype in village dogs across the world, including those from Central America, the Middle East, South Asia, and the French Polynesian Islands. Among the 31 breed dogs we see it in, we see it in Poodles, Otterhounds, and Labrador Retrievers. It is also our most commonly-sampled Golden Retriever haplotype!

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Roxanne inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Roxanne is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.