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Rosie TKN TKI

Mixed Ancestry

“AKC-Galano’s Every Rose Has It’s Thorn TKI A fun loving pup living a wonderful life in the northeast”

Instagram tag
@rosie.the.rescue.mix

Place of Birth

New Orleans, Louisiana, USA

Current Location

Weymouth, Massachusetts, USA

From

shelter near St. Roch, New Orleans, LA, USA

This dog has been viewed and been given 7 wags

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Australian Shepherd

Australian Shepherds are an energetic mid-sized breed that make the perfect companion.

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Golden Retriever

Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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American Eskimo Dog

American Eskimo Dogs belong to the spitz family and they actually came from Germany. They got their start in American circuses due to their intelligence. Today, Eskies make wonderful family pets.

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Cocker Spaniel

Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.

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Dogs Like Rosie

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Discover dogs who share a similar breed mix to Rosie. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Labrador Retriever
Australian Shepherd
Golden Retriever
Boxer
German Shepherd Dog
American Eskimo Dog
Cocker Spaniel
Supermutt

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Here’s what Rosie’s family tree may have looked like.
Rosie
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed Labrador Retriever / Golden Retriever mix Boxer / Cocker Spaniel mix Australian Shepherd / American Eskimo Dog mix Labrador Retriever / German Shepherd Dog mix Labrador Retriever Golden Retriever Boxer Cocker Spaniel mix Australian Shepherd American Eskimo Dog mix Labrador Retriever mix German Shepherd Dog mix
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Rosie’s breed mix.

Breed Reveal Video

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Health Summary

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Rosie is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Rosie inherited one copy of the variant we tested

How to interpret this result

Rosie has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Rosie inherited one copy of the variant we tested

Why is this important to your vet?

Rosie has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Rosie has this genotype, as ALT is often used as an indicator of liver health and Rosie is likely to have a lower than average resting ALT activity. As such, an increase in Rosie’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Shepherds and German Shepherd Dogs

Hemophilia A

Identified in Boxers

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Thrombopathia

Identified in American Eskimo Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Platelet Factor X Receptor Deficiency, Scott Syndrome

Identified in German Shepherd Dogs

Progressive Retinal Atrophy, prcd

Identified in American Eskimo Dogs, Australian Shepherds, and more

Golden Retriever Progressive Retinal Atrophy 1, GR-PRA1

Identified in Golden Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Golden Retrievers and Labrador Retrievers

Progressive Retinal Atrophy, crd4/cord1

Identified in Labrador Retrievers

Collie Eye Anomaly

Identified in Australian Shepherds

Day Blindness

Identified in German Shepherd Dogs

Day Blindness

Identified in Labrador Retrievers

Canine Multifocal Retinopathy, cmr1

Identified in Australian Shepherds

Hereditary Cataracts

Identified in Australian Shepherds

Primary Lens Luxation

Identified in American Eskimo Dogs

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones

Identified in Australian Shepherds, German Shepherd Dogs, and more

Familial Nephropathy

Identified in Cocker Spaniels

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency

Identified in Cocker Spaniels

Neuronal Ceroid Lipofuscinosis 6, NCL 6

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Shepherds

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Golden Retrievers

Alexander Disease

Identified in Labrador Retrievers

Degenerative Myelopathy, DM

Identified in American Eskimo Dogs, Australian Shepherds, and more

Narcolepsy

Identified in Labrador Retrievers

Acral Mutilation Syndrome

Identified in Cocker Spaniels

Muscular Dystrophy

Identified in Golden Retrievers

Ullrich-like Congenital Muscular Dystrophy

Identified in Labrador Retrievers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Cocker Spaniels and Labrador Retrievers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Golden Retrievers

Dystrophic Epidermolysis Bullosa

Identified in Golden Retrievers

Ichthyosis, ICH1

Identified in Golden Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Osteogenesis Imperfecta

Identified in Golden Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Craniomandibular Osteopathy, CMO

Identified in Australian Shepherds

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Rosie’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B81/84

Map

B1

Rosie’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B81/84

Rosie’s Haplotype

Part of the B1 haplogroup, this haplotype occurs most frequently in Golden Retrievers, Poodles, Yorkshire Terriers, Chihuahuas, and Beagles.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Rosie inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Rosie is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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