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Roscoe

Chinese Shar-Pei

No bio has been provided yet

Current Location

Columbus, Ohio, USA

From

Toledo, OH, USA

This dog has been viewed and been given 12 wags

Genetic Breed Result

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Chinese Shar-Pei

Few dog breeds are more recognizable than the wrinkly Chinese Shar-Pei. This Chinese breed is often compared to a hippopotamus due to its thick muzzle. They also have a characteristic rough, bristly coat, which is how the breed got its name (“Shar-Pei” means “sand skin”). Despite their goofy appearance, Shar-Peis are serious, independent dogs who will loyally protect their owners.

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Here’s what Roscoe’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Roscoe’s breed mix.

Breed Reveal Video

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Health Summary

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Roscoe is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Shar-Pei Autoinflammatory Disease, SPAID, Shar-Pei Fever

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Roscoe inherited one copy of the variant we tested

How to interpret this result

Roscoe has one copy of a variant in the MTBP gene and is considered at risk for developing SPAID. More commonly known as Familial Shar-Pei Fever, this condition causes recurrent high fevers and joint swelling and pain. Some Shar-Peis will also develop an inappropriate accumulation of protein in the liver and kidneys. This variant likely has an incomplete dominant inheritance in the Shar-Pei, meaning that Shar-Peis with one copy of the variant are at lower risk when compared to dogs with two copies of the variant, but at greater risk than dogs with no copies of the variant. Please consult with your veterinarian to discuss further diagnostic, treatment, and monitoring options for Roscoe.

What is Shar-Pei Autoinflammatory Disease, SPAID, Shar-Pei Fever?

More commonly known as Familial Shar-Pei Fever, this autoinflammatory condition causes recurrent high fevers, joint swelling and pain, and overall malaise. Some Shar-Peis will also develop amyloidosis, an inappropriate accumulation of an abnormal protein, amyloid, in the liver and kidneys.

Primary Open Angle Glaucoma and Primary Lens Luxation

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Roscoe inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Roscoe’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Roscoe is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Primary Open Angle Glaucoma and Primary Lens Luxation?

Glaucoma is the result of high intraocular pressure, and if left untreated, can lead to pain and vision loss. The "angle" of primary open glaucoma (POAG) refers to the intersection of the cornea and the iris: this is where aqueous humor (clear fluid filling the eye) must flow to exit the eye. In open angle glaucoma, the iridocorneal angle remains unchanged, and other factors contribute to increased resistance to outflow.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Roscoe’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B77

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B1

Roscoe’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B77

Roscoe’s Haplotype

Part of the B1 haplogroup, this haplotype occurs most frequently in Japanese Chins.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Roscoe’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

Hc.2

Map

A2b

Roscoe’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

Hc.2

Roscoe’s Haplotype

Part of the A2b haplogroup, this haplotype has been found in Chinese Shar-pei and village dogs in Papua New Guinea.

A2b is found in the Daschund breed.

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