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Roscoe

Mixed Ancestry

“He is a gentle giant who would rather lick you than bark at you. A great foot warmer and loyal friend. He was even featured in a book!”

Place of Birth

Virginia, USA

Current Location

Bristow, Virginia, USA

From

Washington, DC, USA

This dog has been viewed and been given 14 wags

Genetic Breed Result

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Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Russell-type Terrier

These small, energetic terriers, developed in 19th century England for hunting small game, are now some of the best agility dogs around.

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Dogs Like Roscoe

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Discover dogs who share a similar breed mix to Roscoe. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Beagle
Russell-type Terrier

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Here’s what Roscoe’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Roscoe’s breed mix.
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Health Summary

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Roscoe is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Roscoe inherited both copies of the variant we tested

How to interpret this result

Roscoe has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Factor VII Deficiency

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Roscoe inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Roscoe’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Roscoe is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Factor VII Deficiency?

Factor VII deficiency is a type of coagulopathy, a disorder of blood clotting. It is characterized by mild to moderate abnormal bleeding (generally less severe than that caused by deficiencies in other clotting factors such as Factors VIII or IX). Some dogs with this condition will show no clinical signs.

Degenerative Myelopathy, DM

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Roscoe inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Roscoe’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Roscoe is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Breed-Relevant Genetic Conditions

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Pyruvate Kinase Deficiency

Identified in Beagles

Severe Combined Immunodeficiency, SCID

Identified in Russell-type Terriers

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles

Primary Open Angle Glaucoma

Identified in Beagles

Primary Lens Luxation

Identified in Russell-type Terriers

Urate Kidney & Bladder Stones

Identified in Russell-type Terriers

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Late Onset Spinocerebellar Ataxia

Identified in Russell-type Terriers

Spinocerebellar Ataxia with Myokymia and/or Seizures

Identified in Russell-type Terriers

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

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Other Coat Traits

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Through Roscoe’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Roscoe’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Roscoe’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

A1b is the most common haplogroup found in German Shepherds.

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Through Roscoe’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.29

Map

A1a

Roscoe’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.29

Roscoe’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Dogs with A1a lineage travelled during European Colonial times.

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