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Romo

Mixed Breed

“He’s a rescue who loves his food and squeaky toys. We’re so lucky to have found him.”

Location
Yakima, Washington, USA
From
Moses Lake, WA, USA

This dog has been viewed 261 times and been given 0 wags

Genetic Breed Result

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Mixed Breed

50.0% Pug
20.3% Border Collie
10.8% Golden Retriever
10.2% English Springer Spaniel
8.7% Boxer
Pug Pug
The Pug is a breed of dog with a wrinkly, short-muzzled face and curled tail. Pugs are known for being sociable and gentle companion dogs.
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Border Collie Border Collie
Border Collies are highly energetic and work oriented herding dogs, whose stamina is matched by their intelligence and alertness. If you want the smartest dog out there, then you have come to the right place!
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Golden Retriever Golden Retriever
Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.
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English Springer Spaniel English Springer Spaniel
English Springer Spaniels are an energetic and loyal companion dog, bred for hunting but also popular among families.
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Boxer Boxer
Developed in Germany, the Boxer is a popular family dog-patient, loyal and smart-requiring lots of exercise and proper training.
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Genetic Stats


Wolfiness:

0.6 % LOW

Predicted Adult Weight:

37 lbs

Genetic Age:

45 human years

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Romo’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Pug
Border Collie
Golden Retriever
English Springer Spaniel
Boxer

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

Explore by tapping the parents and grandparents.
 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Pug Border Collie / English Springer Spaniel mix Golden Retriever / Boxer mix Pug Pug Border Collie English Springer Spaniel Golden Retriever Boxer mix Pug Pug Pug Pug

Our algorithms predict this is the most likely family tree to explain Romo’s breed mix, but this family tree may not be the only possible one.

Summary

0
AT RISK
0
CARRIER
166
CLEAR
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Clinical Traits

These clinical traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase (ALT) Activity result: Low Normal

Romo has two copies of a mutation associated with reduced ALT activity. Please inform your veterinarian that Romo has this genotype, as ALT is often used as an indicator of liver health and Romo is likely to have a lower than average resting ALT activity. As such, an increase in Romo’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

Genetic Health Conditions

A genetic health condition indicates a genetic mutation that increases the risk that an animal develops a specific disease.

Not At Risk

Good news! Romo did not test positive for any of the genetic diseases that Embark screens for.

It is still important to let your veterinarian know these results because they could help guide Romo’s diagnosis and treatment if he gets sick in the future.

Not A Carrier

Good news! Romo is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Romo tested clear for 27 genetic conditions that are common in his breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Border Collies, but not Romo.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 10, Boxer Variant)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in Boxers, but not Romo.

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Boxers, but not Romo.

Cyclic Neutropenia, Gray Collie Syndrome
(AP3B1 Exon 20)
Blood

This is a disease of neutrophil, a type of white blood cell, production, where the number of circulating neutrophils drops precipitously, leaving dogs prone to bacterial …

Seen in Border Collies, but not Romo.

May-Hegglin Anomaly
(MYH9)
Blood

A rare, benign disease of platelets, this is characterized by abnormally sparse, large platelets. Your vet may also notice blue blotches known as “inclusion bodies" in so…

Seen in Pugs, but not Romo.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Pug Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Pugs, but not Romo.

Trapped Neutrophil Syndrome
(VPS13B)
Blood

Dogs with TNS are prone to recurrent bacterial infections that must be recognized and treated early. Neutrophils, a type of white blood cells, are generated in the bone m…

Seen in Border Collies, but not Romo.

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Golden Retrievers, but not Romo.

Golden Retriever Progressive Retinal Atrophy 1
(SLC4A3)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Golden Retrievers, but not Romo.

Golden Retriever Progressive Retinal Atrophy 2
(TTC8)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Golden Retrievers, but not Romo.

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in English Springer Spaniels, but not Romo.

Collie Eye Anomaly, Choroidal Hypoplasia
(NHEJ1)
Eyes

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia and is a developmental disease of the choroid. The ch…

Seen in Border Collies, but not Romo.

Autosomal Recessive Hereditary Nephropathy, Familial Nephropathy
(COL4A4 Exon 3)
Kidney and Bladder

This condition causes inappropriate loss of protein in the urine, which leads to muscle wasting, abnormal fluid accumulation in the skin and limbs, and excessive thirst a…

Seen in English Springer Spaniels, but not Romo.

Canine Fucosidosis
(FUCA1)
Multisystem

This form of lysosomal storage disease can cause progressive neurologic dysfunction. Lysosomes are highly specialized organelles: their job is to digest and recycle cellu…

Seen in English Springer Spaniels, but not Romo.

Glycogen storage disease Type VII, Phosphofructokinase deficiency
(PFKM Whippet and English Springer Spaniel Variant)
Multisystem

Affecting an enzyme required for red blood cell and skeletal muscle cell energy production, phosphofructokinase (PFK) deficiency causes red blood cells and skeletal muscl…

Seen in English Springer Spaniels, but not Romo.

Neuronal Ceroid Lipofuscinosis 1
(CLN5 Border Collie Variant)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Border Collies, but not Romo.

Neuronal Ceroid Lipofuscinosis
(CLN5 Golden Retriever Variant)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Golden Retrievers, but not Romo.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Pugs, Border Collies, Golden Retrievers, English Springer Spaniels, Boxers, but not Romo.

Shaking Puppy Syndrome, X-linked Generalized Tremor Syndrome
(PLP)
Brain and Spinal Cord

This group of diseases center around the neuronal axon, a specialized cellular structure that helps our nervous systems relay information across great distances. Remember…

Seen in English Springer Spaniels, but not Romo.

Hereditary Sensory Autonomic Neuropathy (HSAN), Acral Mutilation Syndrome
(GDNF-AS)
Brain and Spinal Cord

A rare condition affecting the ability to feel pain, HSAN has been diagnosed in French Spaniels, English Springer Spaniels, English Pointers, and German Shorthaired Point…

Seen in English Springer Spaniels, but not Romo.

Long QT Syndrome
(KCNQ1)
Heart

A rare heart disease first characterized in the English Springer Spaniel, this can cause sudden collapse and seizures but is responsive to medical management. The “QT” in…

Seen in English Springer Spaniels, but not Romo.

Muscular Dystrophy
Muscular Dystrophy (DMD Golden Retriever Variant)
Muscular

Characterized by non-painful muscle weakness and wasting, early diagnosis and supportive treatment can slow the pace of this progressive muscle disease. All known mutatio…

Seen in Golden Retrievers, but not Romo.

Myotonia Congenita
(CLCN1 Exon 23)
Muscular

This condition is characterized by prolonged muscle contraction and stiffness that usually resolves with normal exercise, though physical therapy can be beneficial. The g…

Seen in Border Collies, but not Romo.

Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption
(CUBN Exon 53)
Gastrointestinal

This is a treatable gastrointestinal disease where dogs cannot absorb cobalamin, often causing them to be runty with poor energy levels. Cobalamin is required for synthes…

Seen in Border Collies, but not Romo.

Dystrophic Epidermolysis Bullosa
(COL7A1)
Skin & Connective Tissues

This skin disorder gives affected dogs skin that stretches and tears easily; affected dogs must be monitored closely and treated promptly for any injuries. It arises from…

Seen in Golden Retrievers, but not Romo.

Ichthyosis
(PNPLA1)
Skin & Connective Tissues

This skin disorder gets its name from the thick, darkly pigmented scales of skin (“ichthys” is Greek for “fish”) that affected dogs display on their noses, paw pads, and …

Seen in Golden Retrievers, but not Romo.

Osteogenesis Imperfecta, Brittle Bone Disease
(COL1A1)
Skeletal

A disease of bone strength and flexibilty, affected dogs often present to the vet for spontaneous bone fractures, tooth fractures and loss, and joint pain; these symptoms…

Seen in Golden Retrievers, but not Romo.

Other Conditions:
Clear of 139

Romo is clear of 139 other genetic diseases that Embark tests for.
Explore the genetics behind your dog’s appearance, size, and genetic diversity.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have a mostly solid black or brown fur coat
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
Can have black masking (dark facial fur)
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Smaller
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Intermediate
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance

Through Romo’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A254

Map

A1a

Romo’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A254

Romo’s Haplotype

Part of the large A1a haplogroup, haplotype has been spotted in village dogs in Peru. As for breed dogs, it is most common in Bichon Frise, Pugs, and Miniature Schnauzers.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

Through Romo’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2a

Haplotype

Hc.5

Map

A2a

Romo’s Haplogroup

A2a is a truly ancient lineage. Unlike the recent upstart A1 lineages which found their way from a few popular European males a couple hundred years ago into many dogs in many breeds, A2a shows ancient roots without major recent expansion. It is likely one of the oldest eastern Eurasian male lineages of dogs, where it has existed for thousands of years. Nowadays, it's commonly found in Tibetan Terriers and Chow Chows as well as in Southeastern Asian village dogs. The Chow Chow seems to have been depicted in sculpture over 2,000 years ago, so this is an ancient lineage indeed, and dogs with it have a long and noble pedigree! Males from this lineage have continued to be bred in similar forms and breeds for millennia.

Hc.5

Romo’s Haplotype

Part of the A2a haplogroup, this haplotype occurs most commonly in Chow Chows and village dogs from Papua New Guinea.

Some other Embark dogs with this haplotype:

The large-sized Tibetan Mastiff descends from this ancient lineage.