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Cardigan Welsh Corgi

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Current Location

Williston, Florida, USA

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Registration

American Kennel Club (AKC): DN27007101

Genetic Breed Result

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Cardigan Welsh Corgi

Though less common than their Pembroke cousins, the Cardigan Welsh Corgi is perfectly suited to move cattle, as well as be a smart, driven companion for the right people. This breed is highly trainable, and often compared to a German Shepherd Dog in drive and attitude. Cardigans have the bark of a much bigger dog!

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Genetic Stats

Predicted Adult Weight

39 lbs

Genetic Age
87 human years

Based on the date of birth provided

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Health Summary

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LEO is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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LEO inherited both copies of the variant we tested

How to interpret this result

LEO has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Dilated Cardiomyopathy, DCM2

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LEO inherited one copy of the variant we tested

What does this result mean?

Research indicates that this genetic variant is not likely to increase the risk that LEO will develop this condition.

Scientific Basis

Dogs with LEO’s breed have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of LEO developing clinical disease.

Impact on Breeding

This genetic result should not be the primary factor in your breeding decisions.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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LEO inherited one copy of the variant we tested

Why is this important to your vet?

LEO has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that LEO has this genotype, as ALT is often used as an indicator of liver health and LEO is likely to have a lower than average resting ALT activity. As such, an increase in LEO’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Cardigan Welsh Corgis

X-linked Severe Combined Immunodeficiency, X-SCID (IL2RG, Corgi Variant)

Identified in Cardigan Welsh Corgis

Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Cardigan Welsh Corgis

Degenerative Myelopathy, DM (SOD1A)

Identified in Cardigan Welsh Corgis

Exercise-Induced Collapse, EIC (DNM1)

Identified in Cardigan Welsh Corgis

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

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Body Size

Performance

Performance

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Through LEO’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A385

Map

A1a

RIVERSIDE IT’S A NEW YEAR BOSS’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A385

RIVERSIDE IT’S A NEW YEAR BOSS’s Haplotype

Part of the A1a haplogroup, the A385 haplotype occurs most commonly in Irish Terriers and Cardigan Welsh Corgis.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Through LEO’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.14

Map

A1a

RIVERSIDE IT’S A NEW YEAR BOSS’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.14

RIVERSIDE IT’S A NEW YEAR BOSS’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs mainly in village dogs from Central and South Americas, but has also been spotted in Papua New Guinea. It also occurs frequently in Cocker Spaniels, English Cocker Spaniels, and Pembroke Welsh Corgis.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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