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River

McNab

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Place of Birth

Inkom, ID, USA

Current Location

Tooele, Utah, USA

From

Inkom, ID, USA

This dog has been viewed and been given 9 wags

Genetic Breed Result

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McNab

McNabs are an interesting breed of herding dog that originated in the Mendocino region of Northern California. It should be noted that it’s quite rare to be able to pinpoint such a specific place of origin for a dog breed from the United States. They were specifically created to withstand the scorching heat of the Mendocino region of California.

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain River’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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River inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Collie Eye Anomaly

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River inherited one copy of the variant we tested

What does this result mean?

This result does not impact your dog’s health. It could have consequences for siblings or other family members, and you should let them know if you are in contact with them. This result is also important if you decide to breed this dog - to produce the healthiest puppies we recommend genetic testing any potential mates for this condition.

What is Collie Eye Anomaly?

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia. The choroid anchors the retina to the underlying structures and supplies it with oxygen and nourishment. CEA is a developmental disease of the choroid.

ALT Activity

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River inherited one copy of the variant we tested

Why is this important to your vet?

River has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that River has this genotype, as ALT is often used as an indicator of liver health and River is likely to have a lower than average resting ALT activity. As such, an increase in River’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Trapped Neutrophil Syndrome, TNS

Primary Lens Luxation

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Myotonia Congenita

Cobalamin Malabsorption

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through River’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A236

Map

A1e

River’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A236

River’s Haplotype

Part of the large A1e haplogroup, this haplotype occurs most commonly in Border Collies. It’s a rare find!

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that River inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since River is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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